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Volume 23, Number 1—January 2017

CME ACTIVITY - Research

Analysis of Anthrax Immune Globulin Intravenous with Antimicrobial Treatment in Injection Drug Users, Scotland, 2009–2010

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Article Title: Analysis of Anthrax Immune Globulin Intravenous with Antimicrobial Treatment in Injection Drug Users, Scotland, 2009–2010

CME Questions

1. What should you consider regarding the response to severe anthrax disease and the application of anthrax immune globulin intravenous (AIG-IV)?

A. Antitoxin agents are most effective as monotherapy

B. AIG-IV is stored as part of the Strategic National Stockpile

C. AIG-IV is derived from bovine hosts

D. AIG-IV has been tested for efficacy among humans

2. Which of the following variables was most associated with receiving AIG-IV among patients in the current study?

A. Higher risk for mortality

B. Male sex

C. Presenting originally with signs of systemic infection

D. Weak microbiologic evidence of infection

3. Which of the following statements regarding the treatment of patients with systemic anthrax in the current study is most accurate?

A. AIG-IV promoted angioedema in approximately 30% of treated patients

B. AIG-IV was associated with increased rates of hypotension

C. Patients treated with AIG-IV were more likely to undergo surgery

D. Patients treated with AIG-IV received less antibiotics

4. Which of the following statements regarding outcomes of treatment with AIG-IV in the current study is most accurate?

A. AIG-IV was associated with a broad survival benefit

B. AIG-IV reduced the risk for mortality only among severely ill patients

C. AIG-IV reduced the risk for mortality only among individuals with moderate illness

D. Treatment with AIG-IV was associated with longer stays in the intensive care unit and hospital

Activity Evaluation

1. The activity supported the learning objectives.

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2. The material was organized clearly for learning to occur.

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3. The content learned from this activity will impact my practice.

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4. The activity was presented objectively and free of commercial bias.

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