TY - JOUR AU - Achar, Jay AU - Hewison, Cathy AU - Cavalheiro, Ana AU - Skrahina, Alena AU - Cajazeiro, Junia AU - Nargiza, Parpieva AU - Herboczek, Krzysztof AU - Rajabov, Assliddin AU - Hughes, Jennifer AU - Ferlazzo, Gabriella AU - Seddon, James AU - du Cros, Philipp T1 - Off-Label Use of Bedaquiline in Children and Adolescents with Multidrug-Resistant Tuberculosis T2 - Emerging Infectious Disease journal PY - 2017 VL - 23 IS - 10 SP - 1711 SN - 1080-6059 AB - We describe 27 children and adolescents <18 years of age who received bedaquiline during treatment for multidrug-resistant tuberculosis. We report good treatment responses and no cessation attributable to adverse effects. Bedaquiline could be considered for use with this age group for multidrug-resistant tuberculosis when treatment options are limited. KW - MDR TB KW - XDR TB KW - pediatric KW - treatment KW - bedaquiline KW - tuberculosis KW - multidrug resistance KW - bacteria KW - antimicrobial resistance KW - respiratory infections KW - off-label use KW - United Kingdom KW - France KW - Tajikistan KW - Belarus KW - Uzbekistan KW - Mycobacterium tuberculosis KW - multidrug-resistant tuberculosis KW - children KW - adolescents KW - TB KW - South Africa DO - 10.3201/eid2310.170303 UR - https://wwwnc.cdc.gov/eid/article/23/10/17-0303_article ER - End of Reference