TY - JOUR AU - Cui, Fuqiang AU - Shen, Lipin AU - Li, Li AU - Wang, Huaqing AU - Wang, Fuzhen AU - Bi, Shengli AU - Liu, Jianhua AU - Zhang, Guomin AU - Feng, Zijian AU - Zheng, Hui AU - Sun, Xiaojin AU - Miao, Ning AU - Yin, Zundong T1 - Prevention of Chronic Hepatitis B after 3 Decades of Escalating Vaccination Policy, China T2 - Emerging Infectious Disease journal PY - 2017 VL - 23 IS - 5 SP - 765 SN - 1080-6059 AB - China’s hepatitis B virus (HBV) prevention policy has been evaluated through nationally representative serologic surveys conducted in 1992 and 2006. We report results of a 2014 serologic survey and reanalysis of the 1992 and 2006 surveys in the context of program policy. The 2014 survey used a 2-stage sample strategy in which townships were selected from 160 longstanding, nationally representative, county-level disease surveillance points, and persons 1–29 years of age were invited to participate. The 2014 sample size was 31,713; the response rate was 83.3%. Compared with the 1992 pre–recombinant vaccine survey, HBV surface antigen prevalence declined 46% by 2006 and by 52% by 2014. Among children <5 years of age, the decline was 97%. China’s HBV prevention program, targeted toward interrupting perinatal transmission, has been highly successful and increasingly effective. However, this progress must be sustained for decades to come, and elimination of HBV transmission will require augmented strategies. KW - hepatitis B KW - vaccine KW - vaccination KW - immunization KW - China KW - viruses DO - 10.3201/eid2305.161477 UR - https://wwwnc.cdc.gov/eid/article/23/5/16-1477_article ER - End of Reference