TY - JOUR AU - Herbst, Allen AU - Velásquez, Camilo Duque AU - Triscott, Elizabeth AU - Aiken, Judd AU - McKenzie, Debbie T1 - Chronic Wasting Disease Prion Strain Emergence and Host Range Expansion T2 - Emerging Infectious Disease journal PY - 2017 VL - 23 IS - 9 SP - 1598 SN - 1080-6059 AB - Human and mouse prion proteins share a structural motif that regulates resistance to common chronic wasting disease (CWD) prion strains. Successful transmission of an emergent strain of CWD prion, H95+, into mice resulted in infection. Thus, emergent CWD prion strains may have higher zoonotic potential than common strains. KW - prions KW - prion diseases KW - prions and related diseases KW - host range KW - chronic wasting disease KW - pathogenicity KW - pathogen-host interactions KW - cervids KW - mice KW - zoonoses KW - Canada DO - 10.3201/eid2309.161474 UR - https://wwwnc.cdc.gov/eid/article/23/9/16-1474_article ER - End of Reference