TY - JOUR AU - Safronetz, David AU - Sloan, Angela AU - Stein, Derek AU - Mendoza, Emelissa AU - Barairo, Nicole AU - Ranadheera, Charlene AU - Scharikow, Leanne AU - Holloway, Kimberly AU - Robinson, Alyssia AU - Traykova-Andonova, Maya AU - Makowski, Kai AU - Dimitrova, Kristina AU - Giles, Elizabeth AU - Hiebert, Joanne AU - Mogk, Rhonda AU - Beddome, Sharla AU - Drebot, Michael T1 - Evaluation of 5 Commercially Available Zika Virus Immunoassays T2 - Emerging Infectious Disease journal PY - 2017 VL - 23 IS - 9 SP - 1577 SN - 1080-6059 AB - Because of the global spread of Zika virus, accurate and high-throughput diagnostic immunoassays are needed. We compared the sensitivity and specificity of 5 commercially available Zika virus serologic assays to the recommended protocol of Zika virus IgM-capture ELISA and plaque-reduction neutralization tests. Most commercial immunoassays showed low sensitivity, which can be increased. KW - Zika virus KW - viruses KW - immunoassays KW - evaluation KW - vector-borne infections KW - zoonoses KW - ELISA KW - IgM-capture ELISA KW - MAC-ELISA KW - IgM KW - sensitivity KW - specificity KW - Canada DO - 10.3201/eid2309.162043 UR - https://wwwnc.cdc.gov/eid/article/23/9/16-2043_article ER - End of Reference