TY - JOUR AU - Armstrong, Paige AU - Jackson, Brendan AU - Haselow, Dirk AU - Fields, Virgie AU - Ireland, Malia AU - Austin, Connie AU - Signs, Kimberly AU - Fialkowski, Veronica AU - Patel, Reema AU - Ellis, Peggy AU - Iwen, Peter AU - Pedati, Caitlin AU - Gibbons-Burgener, Suzanne AU - Anderson, Jannifer AU - Dobbs, Thomas AU - Davidson, Sherri AU - McIntyre, Mary AU - Warren, Kimberly AU - Midla, Joanne AU - Luong, Nhiem AU - Benedict, Kaitlin T1 - Multistate Epidemiology of Histoplasmosis, United States, 2011–2014 T2 - Emerging Infectious Disease journal PY - 2018 VL - 24 IS - 3 SP - 425 SN - 1080-6059 AB - Histoplasmosis is one of the most common mycoses endemic to the United States, but it was reportable in only 10 states during 2016, when a national case definition was approved. To better characterize the epidemiologic features of histoplasmosis, we analyzed deidentified surveillance data for 2011–2014 from the following 12 states: Alabama, Arkansas, Delaware, Illinois, Indiana, Kentucky, Michigan, Minnesota, Mississippi, Nebraska, Pennsylvania, and Wisconsin. We examined epidemiologic and laboratory features and calculated state-specific annual and county-specific mean annual incidence rates. A total of 3,409 cases were reported. Median patient age was 49 (interquartile range 33–61) years, 2,079 (61%) patients were male, 1,273 (57%) patients were hospitalized, and 76 (7%) patients died. Incidence rates varied markedly between and within states. The high hospitalization rate suggests that histoplasmosis surveillance underestimates the true number of cases. Improved surveillance standardization and surveillance by additional states would provide more comprehensive knowledge of histoplasmosis in the United States. KW - mycoses KW - fungi KW - histoplasmosis KW - epidemiology KW - surveillance KW - United States DO - 10.3201/eid2403.171258 UR - https://wwwnc.cdc.gov/eid/article/24/3/17-1258_article ER - End of Reference