TY - JOUR AU - Bulens, Sandra AU - Yi, Sarah AU - Walters, Maroya AU - Jacob, Jesse AU - Bower, Chris AU - Reno, Jessica AU - Wilson, Lucy AU - Vaeth, Elisabeth AU - Bamberg, Wendy AU - Janelle, Sarah AU - Lynfield, Ruth AU - Vagnone, Paula Snippes AU - Shaw, Kristin AU - Kainer, Marion AU - Muleta, Daniel AU - Mounsey, Jacqueline AU - Dumyati, Ghinwa AU - Concannon, Cathleen AU - Beldavs, Zintars AU - Cassidy, P. Maureen AU - Phipps, Erin AU - Kenslow, Nicole AU - Hancock, Emily AU - Kallen, Alexander T1 - Carbapenem-Nonsusceptible Acinetobacter baumannii, 8 US Metropolitan Areas, 2012–2015 T2 - Emerging Infectious Disease journal PY - 2018 VL - 24 IS - 4 SP - 727 SN - 1080-6059 AB - In healthcare settings, Acinetobacter spp. bacteria commonly demonstrate antimicrobial resistance, making them a major treatment challenge. Nearly half of Acinetobacter organisms from clinical cultures in the United States are nonsusceptible to carbapenem antimicrobial drugs. During 2012–2015, we conducted laboratory- and population-based surveillance in selected metropolitan areas in Colorado, Georgia, Maryland, Minnesota, New Mexico, New York, Oregon, and Tennessee to determine the incidence of carbapenem-nonsusceptible A. baumannii cultured from urine or normally sterile sites and to describe the demographic and clinical characteristics of patients and cases. We identified 621 cases in 537 patients; crude annual incidence was 1.2 cases/100,000 persons. Among 598 cases for which complete data were available, 528 (88.3%) occurred among patients with exposure to a healthcare facility during the preceding year; 506 (84.6%) patients had an indwelling device. Although incidence was lower than for other healthcare-associated pathogens, cases were associated with substantial illness and death. KW - antimicrobial resistance KW - carbapenems KW - carbapenem-nonsusceptible KW - surveillance KW - prevention KW - bacteria KW - Acinetobacter baumannii KW - Acinetobacter infections KW - United States KW - Emerging Infections Program DO - 10.3201/eid2404.171461 UR - https://wwwnc.cdc.gov/eid/article/24/4/17-1461_article ER - End of Reference