TY - JOUR AU - Cohen, Regev AU - Babushkin, Frida AU - Shapiro, Maurice AU - Uda, Martina AU - Atiya-Nasagi, Yafit AU - Klein, Dar AU - Finn, Talya T1 - Two Cases of Israeli Spotted Fever with Purpura Fulminans, Sharon District, Israel T2 - Emerging Infectious Disease journal PY - 2018 VL - 24 IS - 5 SP - 835 SN - 1080-6059 AB - We report a series of 5 case-patients who had Israeli spotted fever, of whom 2 had purpura fulminans and died. Four case-patients were given a diagnosis on the basis of PCR of skin biopsy specimens 3–4 days after treatment with doxycycline; 1 case-patient was given a diagnosis on the basis of seroconversion. Rickettsia spp. from the 2 case-patients who died were sequenced and identified as Rickettsia conorii subsp. israelensis. Purpura fulminans has been described in association with R. rickettsii and R. indica, but rarely with R. conorii subsp. israelensis. KW - Israeli spotting fever KW - Rickettsia conorii subsp. israelensis KW - rickettsia KW - case series KW - purpura fulminans KW - Sharon District KW - Israel KW - vector-borne infections KW - zoonoses DO - 10.3201/eid2405.171992 UR - https://wwwnc.cdc.gov/eid/article/24/5/17-1992_article ER - End of Reference