TY - JOUR AU - Behar, Adi AU - Baker, Kate Susan AU - Bassal, Ravit AU - Ezernitchi, Analia AU - Valinsky, Lea AU - Thomson, Nicholas AU - Cohen, Daniel T1 - Microevolution and Patterns of Transmission of Shigella sonnei within Cyclic Outbreaks Shigellosis, Israel T2 - Emerging Infectious Disease journal PY - 2018 VL - 24 IS - 7 SP - 1335 SN - 1080-6059 AB - Whole-genome sequencing unveiled host and environment-related insights to Shigella sonnei transmission within cyclic epidemics during 2000–2012 in Israel. The Israeli reservoir contains isolates belonging to S. sonnei lineage III but of different origin, shows loss of tetracycline resistance genes, and little genetic variation within the O antigen: highly relevant for Shigella vaccine development. KW - Whole genome sequencing KW - Shigella sonnei KW - shigellosis KW - ultraorthodox Jews KW - secular Jews KW - Israeli Arabs KW - person-to-person transmission KW - overcrowding KW - children KW - migration KW - Bedouin KW - Beer Sheva KW - Mevaseret KW - Zion KW - Israel KW - Whole-genome sequencing KW - flexneri KW - microevolution KW - tetracycline DO - 10.3201/eid2407.171313 UR - https://wwwnc.cdc.gov/eid/article/24/7/17-1313_article ER - End of Reference