TY - JOUR AU - Andreani, Julien AU - Fongue, Jessica AU - Bou Khalil, Jacques AU - David, Laurene AU - Mougari, Saïd AU - Le Bideau, Marion AU - Abrahão, Jonatas AU - Berbis, Philippe AU - La Scola, Bernard T1 - Human Infection with Orf Virus and Description of Its Whole Genome, France, 2017 T2 - Emerging Infectious Disease journal PY - 2019 VL - 25 IS - 12 SP - 2197 SN - 1080-6059 AB - Zoonotic transmission of parapoxvirus from animals to humans has been reported; clinical manifestations are skin lesions on the fingers and hands after contact with infected animals. We report a human infection clinically suspected as being ecthyma contagiosum. The patient, a 65-year-old woman, had 3 nodules on her hands. She reported contact with a sheep during the Aïd-el-Fitr festival in France during 2017. We isolated the parapoxvirus orf virus from these nodules by using a nonconventional cell and sequenced the orf genome. We identified a novel orf virus genome and compared it with genomes of other orf viruses. More research is needed on the genus Parapoxvirus to understand worldwide distribution of and infection by orf virus, especially transmission between goats and sheep. KW - orf virus KW - viruses KW - poxviridae KW - human infection KW - Aïd-el-Fitr KW - festival KW - case report KW - whole-genome sequencing KW - France KW - phylogenetic analysis KW - ecthyma contagiosum KW - sheep DO - 10.3201/eid2512.181513 UR - https://wwwnc.cdc.gov/eid/article/25/12/18-1513_article ER - End of Reference