TY - JOUR AU - Grome, Heather AU - Threlkeld, Michael AU - Threlkeld, Steve AU - Newman, Charles AU - Martines, Roosecelis Brasil AU - Reagan-Steiner, Sarah AU - Whitt, Michael AU - Gomes-Solecki, Maria AU - Nair, Nisha AU - Fill, Mary-Margaret AU - Jones, Timothy AU - Schaffner, William AU - Dunn, John T1 - Fatal Multisystem Inflammatory Syndrome in Adult after SARS-CoV-2 Natural Infection and COVID-19 Vaccination T2 - Emerging Infectious Disease journal PY - 2021 VL - 27 IS - 11 SP - 2914 SN - 1080-6059 AB - We describe a fatal case of multisystem inflammatory syndrome in an adult with onset 22 days after a second dose of mRNA coronavirus disease vaccine. Serologic and clinical findings indicated severe acute respiratory syndrome coronavirus 2 infection occurred before vaccination. The immunopathology of this syndrome, regardless of vaccination status, remains poorly understood. KW - COVID-19 KW - coronavirus disease KW - SARS-CoV-2 KW - severe acute respiratory syndrome coronavirus 2 KW - viruses KW - respiratory infections KW - multisystem inflammatory syndrome in adults KW - MIS-A KW - vaccines KW - vaccine-preventable diseases DO - 10.3201/eid2711.211612 UR - https://wwwnc.cdc.gov/eid/article/27/11/21-1612_article ER - End of Reference