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Volume 27, Number 12—December 2021
Research

Characterization of Swine Influenza A(H1N2) Variant, Alberta, Canada, 2020

Jamil N. Kanji1Comments to Author , Kanti Pabbaraju, Matthew Croxen, Susan Detmer, Nathalie Bastien, Yan Li, Anna Majer, Hussein Keshwani, Nathan Zelyas, Ifeoma Achebe, Corinne Jones, Maureen Rutz, Angela Jacobs, Keith Lehman, Deena Hinshaw, and Graham Tipples
Author affiliations: Alberta Precision Laboratories, Edmonton, Alberta, Canada (J.N. Kanji, K. Pabbaraju, M. Croxen, N. Zelyas, G. Tipples); University of Alberta, Edmonton (J.N. Kanji, M. Croxen, N. Zelyas, I. Achebe, D. Hinshaw, G. Tipples); University of Saskatchewan, Regina, Saskatchewan, Canada (S. Detmer); Public Health Agency of Canada, Winnipeg, Manitoba, Canada (N. Bastien, Y. Li, A. Majer); Alberta Agriculture and Forestry, Edmonton (H. Keshwani, K. Lehman); Alberta Health Services, Red Deer, Alberta, Canada (I. Achebe, C. Jones, M. Rutz); Alberta Health Services, Edmonton (A. Jacobs); University of Calgary, Calgary, Alberta, Canada (D. Hinshaw)

Main Article

Table

Genetic comparison of A/Alberta/01/2020 (H1N2)v and other influenza strains in swine and humans, United States and Canada, 2016–2020*

GISAID ID Segment Gene GenBank accession no. % Identity Host Genotype Country Strain Clade
EPI1815176 1 PB2 MK475180 99.3 Human H1N1 USA A/Connecticut/37/2018 npdm
MK475443 99.3 Human H1N1 USA A/Montana/39/2018 npdm



MK623898
99.3
Human
H1N1
USA
A/Wisconsin/517/2018
npdm
EPI1056722



91.4
Human
H1N2v
USA
A/Ohio/24/2017†
H1α-3 variant
EPI1815177
2
PB1
MK631128
99.3
Human
H1N1
USA
A/Iowa/01/2019
npdm
EPI1056723



91.3
Human
H1N2v
USA
A/Ohio/24/2017†
H1α-3 variant
EPI1815175 3 PA MK462359 98.7 Swine H3N2 Canada A/swine/Saskatchewan/ SD0247/2017 Swine H3



MK462496
98.7
Swine
H3N2
Canada
A/swine/Saskatchewan/ SD0258/2017
Swine H3
EPI1056721



96.4
Human
H1N2v
USA
A/Ohio/24/2017†
H1α-3 variant
EPI1815179
4
HA
MK462499
97.9
Swine
H1N2
Canada
A/swine/Alberta/SD0237/2017
H1α-3a
EPI1056725



91.7
Human
H1N2v
USA
A/Ohio/24/2017†
H1α-3 variant
EPI1815172
5
NP
MK445889
99.0
Human
H1N1
USA
A/North Dakota/42/2018
npdm
EPI1056718



94.9
Human
H1N2v
USA
A/Ohio/24/2017†
H1α-3 variant
EPI1815178
6
NA
MK462493
98.2
Swine
H3N2
Canada
A/swine/Saskatchewan/ SD0258/2017
Swine H3
EPI1056724



95.4
Human
H1N2v
USA
A/Ohio/24/2017†
H1α-3 variant
EPI1815174 7 M CY246708 99.5 Swine H1N2 Canada A/swine/Saskatchewan/ SD0204/2016H1N2 H1α-3
CY246716 99.5 Swine H1N2 Canada A/swine/Manitoba/SD0203/ 2016H1N2 H1α-3



MK462355
99.5
Swine
H3N2
Canada
A/swine/Saskatchewan/ SD0247/2017
Swine H3
EPI1056720



96.6
Human
H1N2v
Canada
A/Ohio/24/2017†
H1α-3 variant
EPI1815173
8
NS
MK462463
99.2
Swine
H1N2
Canada
A/swine/Alberta/SD0267/2017
H1α-3a
EPI1056719 94.1 Human H1N2v USA A/Ohio/24/2017† H1α-3 variant

*GISAID, https://www.gisaid.org. HA, hemagglutinin; ID, identification; M, matrix; NA, neuraminidase; NP, nucleoprotein; npdm, influenza A(H1N1)pdm09-like virus; NS, nonstructural protein; PA, polymerase acidic protein; PB1, polymerase base protein 1; PB2, polymerase basic protein 2. †A/Ohio/24/2017 data was deposited into GISAID by the Centers for Disease Control (Atlanta, Georgia, USA) and first identified in the Ohio Department of Health Laboratories (Reynoldsburg, Ohio, USA).

Main Article

1Current affiliation: University of Calgary, Calgary, Alberta, Canada.

Page created: September 28, 2021
Page updated: November 19, 2021
Page reviewed: November 19, 2021
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