Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 27, Number 12—December 2021
Research

Characterization of Swine Influenza A(H1N2) Variant, Alberta, Canada, 2020

Jamil N. Kanji1Comments to Author , Kanti Pabbaraju, Matthew Croxen, Susan Detmer, Nathalie Bastien, Yan Li, Anna Majer, Hussein Keshwani, Nathan Zelyas, Ifeoma Achebe, Corinne Jones, Maureen Rutz, Angela Jacobs, Keith Lehman, Deena Hinshaw, and Graham Tipples
Author affiliations: Alberta Precision Laboratories, Edmonton, Alberta, Canada (J.N. Kanji, K. Pabbaraju, M. Croxen, N. Zelyas, G. Tipples); University of Alberta, Edmonton (J.N. Kanji, M. Croxen, N. Zelyas, I. Achebe, D. Hinshaw, G. Tipples); University of Saskatchewan, Regina, Saskatchewan, Canada (S. Detmer); Public Health Agency of Canada, Winnipeg, Manitoba, Canada (N. Bastien, Y. Li, A. Majer); Alberta Agriculture and Forestry, Edmonton (H. Keshwani, K. Lehman); Alberta Health Services, Red Deer, Alberta, Canada (I. Achebe, C. Jones, M. Rutz); Alberta Health Services, Edmonton (A. Jacobs); University of Calgary, Calgary, Alberta, Canada (D. Hinshaw)

Main Article

Table

Genetic comparison of A/Alberta/01/2020 (H1N2)v and other influenza strains in swine and humans, United States and Canada, 2016–2020*

GISAID ID Segment Gene GenBank accession no. % Identity Host Genotype Country Strain Clade
EPI1815176 1 PB2 MK475180 99.3 Human H1N1 USA A/Connecticut/37/2018 npdm
MK475443 99.3 Human H1N1 USA A/Montana/39/2018 npdm
MK623898
 99.3
 Human
 H1N1
 USA
 A/Wisconsin/517/2018
 npdm
EPI1056722
91.4
 Human
 H1N2v
 USA
 A/Ohio/24/2017†
 H1α-3 variant
EPI1815177
 2
 PB1
 MK631128
 99.3
 Human
 H1N1
 USA
 A/Iowa/01/2019
 npdm
EPI1056723
91.3
 Human
 H1N2v
 USA
 A/Ohio/24/2017†
 H1α-3 variant
EPI1815175 3 PA MK462359 98.7 Swine H3N2 Canada A/swine/Saskatchewan/ SD0247/2017 Swine H3
MK462496
 98.7
 Swine
 H3N2
 Canada
 A/swine/Saskatchewan/ SD0258/2017
 Swine H3
EPI1056721
96.4
 Human
 H1N2v
 USA
 A/Ohio/24/2017†
 H1α-3 variant
EPI1815179
 4
 HA
 MK462499
 97.9
 Swine
 H1N2
 Canada
 A/swine/Alberta/SD0237/2017
 H1α-3a
EPI1056725
91.7
 Human
 H1N2v
 USA
 A/Ohio/24/2017†
 H1α-3 variant
EPI1815172
 5
 NP
 MK445889
 99.0
 Human
 H1N1
 USA
 A/North Dakota/42/2018
 npdm
EPI1056718
94.9
 Human
 H1N2v
 USA
 A/Ohio/24/2017†
 H1α-3 variant
EPI1815178
 6
 NA
 MK462493
 98.2
 Swine
 H3N2
 Canada
 A/swine/Saskatchewan/ SD0258/2017
 Swine H3
EPI1056724
95.4
 Human
 H1N2v
 USA
 A/Ohio/24/2017†
 H1α-3 variant
EPI1815174 7 M CY246708 99.5 Swine H1N2 Canada A/swine/Saskatchewan/ SD0204/2016H1N2 H1α-3
CY246716 99.5 Swine H1N2 Canada A/swine/Manitoba/SD0203/ 2016H1N2 H1α-3
MK462355
 99.5
 Swine
 H3N2
 Canada
 A/swine/Saskatchewan/ SD0247/2017
 Swine H3
EPI1056720
96.6
 Human
 H1N2v
 Canada
 A/Ohio/24/2017†
 H1α-3 variant
EPI1815173
 8
 NS
 MK462463
 99.2
 Swine
 H1N2
 Canada
 A/swine/Alberta/SD0267/2017
 H1α-3a
EPI1056719 94.1 Human H1N2v USA A/Ohio/24/2017† H1α-3 variant

*GISAID, https://www.gisaid.org. HA, hemagglutinin; ID, identification; M, matrix; NA, neuraminidase; NP, nucleoprotein; npdm, influenza A(H1N1)pdm09-like virus; NS, nonstructural protein; PA, polymerase acidic protein; PB1, polymerase base protein 1; PB2, polymerase basic protein 2. †A/Ohio/24/2017 data was deposited into GISAID by the Centers for Disease Control (Atlanta, Georgia, USA) and first identified in the Ohio Department of Health Laboratories (Reynoldsburg, Ohio, USA).

Main Article

1Current affiliation: University of Calgary, Calgary, Alberta, Canada.

Page created: September 28, 2021
Page updated: November 19, 2021
Page reviewed: November 19, 2021
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external