TY - JOUR AU - Asgary, Ramin AU - Snead, Jessica AU - Wahid, Nabeel AU - Ro, Vicky AU - Halim, Marina AU - Stribling, Judy T1 - Risks and Preventive Strategies for Clostridioides difficile Transmission to Household or Community Contacts during Transition in Healthcare Settings T2 - Emerging Infectious Disease journal PY - 2021 VL - 27 IS - 7 SP - 1776 SN - 1080-6059 AB - The burden of Clostridioides difficile infection (CDI) has greatly increased. We evaluated the risks for CDI transmission to community members after hospitalized patients are discharged. We conducted a systematic literature review in MEDLINE/PubMed, EMBASE, CINAHL plus EBSCO, Web of Science, Cochrane Library, and gray literature during January 2000‒February 2019 and identified 4,798 citations were identified. We eliminated 4,554 citations through title and abstract screening; 217 additional citations did not meet full criteria. We reviewed texts for the 27 remaining articles qualitatively for internal/external validity. A few identified studies describing risks to community members lacked accurate risk measurement or preventative strategies. Primary data are needed to assess efficacy of and inform current expertise-driven CDI prevention practices. Raising awareness among providers and researchers, conducting clinical and health services research, linking up integrated monitoring and evaluation processes at hospitals and outpatient settings, and developing and integrating CDI surveillance systems are warranted. KW - Clostridioides difficile KW - Clostridioides difficile infection KW - CDI KW - bacteria KW - infection KW - systematic review KW - transmission KW - household KW - community KW - healthcare settings KW - transition KW - risks KW - preventive strategies KW - household contacts KW - community contacts DO - 10.3201/eid2707.200209 UR - https://wwwnc.cdc.gov/eid/article/27/7/20-0209_article ER - End of Reference