TY - JOUR AU - Shah, Melisa AU - Winn, Amber AU - Dahl, Rebecca AU - Kniss, Krista AU - Silk, Benjamin AU - Killerby, Marie T1 - Seasonality of Common Human Coronaviruses, United States, 2014–2021 T2 - Emerging Infectious Disease journal PY - 2022 VL - 28 IS - 10 SP - 1970 SN - 1080-6059 AB - The 4 common types of human coronaviruses (HCoVs)—2 alpha (HCoV-NL63 and HCoV-229E) and 2 beta (HCoV-HKU1 and HCoV-OC43)—generally cause mild upper respiratory illness. Seasonal patterns and annual variation in predominant types of HCoVs are known, but parameters of expected seasonality have not been defined. We defined seasonality of HCoVs during July 2014–November 2021 in the United States by using a retrospective method applied to National Respiratory and Enteric Virus Surveillance System data. In the 6 HCoV seasons before 2020–21, season onsets occurred October 21–November 12, peaks January 6–February 13, and offsets April 18–June 27; most (>93%) HCoV detection was within the defined seasonal onsets and offsets. The 2020–21 HCoV season onset was 11 weeks later than in prior seasons, probably associated with COVID-19 mitigation efforts. Better definitions of HCoV seasonality can be used for clinical preparedness and for determining expected patterns of emerging coronaviruses. KW - coronavirus KW - seasons KW - alphacoronavirus KW - betacoronavirus KW - seasonality KW - viruses KW - United States KW - COVID-19 KW - 2019 novel coronavirus disease KW - coronavirus disease KW - severe acute respiratory syndrome coronavirus 2 KW - SARS-CoV-2 KW - respiratory infections KW - zoonoses DO - 10.3201/eid2810.220396 UR - https://wwwnc.cdc.gov/eid/article/28/10/22-0396_article ER - End of Reference