TY - JOUR AU - Robertson, McKaylee AU - Shamsunder, Meghana AU - Brazier, Ellen AU - Mantravadi, Mekhala AU - Zimba, Rebecca AU - Rane, Madhura AU - Westmoreland, Drew AU - Parcesepe, Angela AU - Maroko, Andrew AU - Kulkarni, Sarah AU - Grov, Christian AU - Nash, Denis T1 - Racial/Ethnic Disparities in Exposure, Disease Susceptibility, and Clinical Outcomes during COVID-19 Pandemic in National Cohort of Adults, United States T2 - Emerging Infectious Disease journal PY - 2022 VL - 28 IS - 11 SP - 2171 SN - 1080-6059 AB - We examined racial/ethnic disparities for COVID-19 seroconversion and hospitalization within a prospective cohort (n = 6,740) in the United States enrolled in March 2020 and followed-up through October 2021. Potential SARS-CoV-2 exposure, susceptibility to COVID-19 complications, and access to healthcare varied by race/ethnicity. Hispanic and Black non-Hispanic participants had more exposure risk and difficulty with healthcare access than white participants. Participants with more exposure had greater odds of seroconversion. Participants with more susceptibility and more barriers to healthcare had greater odds of hospitalization. Race/ethnicity positively modified the association between susceptibility and hospitalization. Findings might help to explain the disproportionate burden of SARS-CoV-2 infections and complications among Hispanic/Latino/a and Black non-Hispanic persons. Primary and secondary prevention efforts should address disparities in exposure, vaccination, and treatment for COVID-19. KW - COVID-19 KW - coronavirus disease KW - severe acute respiratory syndrome coronavirus 2 KW - SARS-CoV-2 KW - coronaviruses KW - viruses KW - respiratory infections KW - racial/ethnic disparities KW - potential virus exposure KW - susceptibility KW - disease KW - healthcare access KW - healthcare disparities KW - clinical outcomes KW - serologic testing KW - social determinants of health KW - zoonoses KW - United States DO - 10.3201/eid2811.220072 UR - https://wwwnc.cdc.gov/eid/article/28/11/22-0072_article ER - End of Reference