TY - JOUR AU - Bostik, Pavel AU - Winter, Jorn AU - Ksiazek, Thomas G. AU - Rollin, Pierre E. AU - Villinger, Francois AU - Zaki, Sherif R. AU - Peters, C.J. AU - Ansari, Aftab A. T1 - Sin Nombre Virus (SNV) Ig Isotype Antibody Response during Acute and Convalescent Phases of Hantavirus Pulmonary Syndrome T2 - Emerging Infectious Disease journal PY - 2000 VL - 6 IS - 2 SP - 184 SN - 1080-6059 AB - Serum samples from 22 hantavirus pulmonary syndrome (HPS) patients were tested for Sin Nombre virus (SNV)-reactive antibodies. In the acute phase of HPS, 100% and 67% of the samples tested positive for SNV-specific immunoglobulin (Ig) M and IgA, respectively. Among the virus-specific IgG antibodies, the most prevalent were IgG3 (in 97% of samples), followed by IgG1 (70%), IgG2 (30%), and IgG4 (3%). KW - hantavirus pulmonary syndrome KW - HPS KW - Sin Nombre virus KW - SNV KW - hantaviruses KW - United States DO - 10.3201/eid0602.000213 UR - https://wwwnc.cdc.gov/eid/article/6/2/00-0213_article ER - End of Reference