TY - JOUR AU - Ijaz, Kashef AU - Yang, Zhenhua AU - Matthews, H. Stewart AU - Bates, Joseph H. AU - Cave, M. Donald T1 - Mycobacterium tuberculosis Transmission between Cluster Members with Similar Fingerprint Patterns T2 - Emerging Infectious Disease journal PY - 2002 VL - 8 IS - 11 SP - 1257 SN - 1080-6059 AB - Molecular epidemiologic studies provide evidence of transmission of Mycobacterium tuberculosis within clusters of patients whose isolates share identical IS6110-DNA fingerprint patterns. However, M. tuberculosis transmission among patients whose isolates have similar but not identical DNA fingerprint patterns (i.e., differing by a single band) has not been well documented. We used DNA fingerprinting, combined with conventional epidemiology, to show unsuspected patterns of tuberculosis transmission associated with three public bars in the same city. Among clustered TB cases, DNA fingerprinting analysis of isolates with similar and identical fingerprints helped us discover epidemiologic links missed during routine tuberculosis contact investigations. KW - Mycobacterium tuberculosis KW - IS6110 RFLP KW - molecular epidemiology KW - tuberculosis transmission KW - bars KW - United States DO - 10.3201/eid0811.020284 UR - https://wwwnc.cdc.gov/eid/article/8/11/02-0284_article ER - End of Reference