TY - JOUR AU - Lok, Kerry H. AU - Benjamin, William H. AU - Kimerling, Michael E. AU - Pruitt, Virginia AU - Mulcahy, Donna AU - Robinson, Nancy AU - Keenan, Nancy B. AU - Dunlap, Nancy E. T1 - Molecular Typing of Mycobacterium tuberculosis Strains with a Common Two-Band IS6110 Pattern T2 - Emerging Infectious Disease journal PY - 2002 VL - 8 IS - 11 SP - 1303 SN - 1080-6059 AB - We conducted a population-based molecular typing of all Mycobacterium tuberculosis isolates obtained in Alabama since 1994. Of 2,452 isolates, 1,013 (41%) had fewer than 6 bands of IS6110; 348 (14%) had a single two-band pattern (JH2). With conventional epidemiologic methods, we identified three groups of related patients with JH2 isolates. Spoligotyping and pattern of variable number of tandem repeats identified 10 molecular groups; two found by conventional methods were subdivided. KW - tuberculosis (TB) genotyping KW - molecular epidemiology KW - homeless KW - variable number of tandem repeats (VNTR) KW - spoligotype KW - United States DO - 10.3201/eid0811.020292 UR - https://wwwnc.cdc.gov/eid/article/8/11/02-0292_article ER - End of Reference