TY - JOUR AU - Olsen, Christopher AU - Brammer, Lynnette AU - Easterday, Bernard C. AU - Arden, Nancy AU - Belay, Ermias AU - Baker, Inger AU - Cox, Nancy J. T1 - Serologic Evidence of H1 Swine Influenza Virus Infection in Swine Farm Residents and Employees T2 - Emerging Infectious Disease journal PY - 2002 VL - 8 IS - 8 SP - 814 SN - 1080-6059 AB - We evaluated seropositivity to swine and human H1 influenza viruses in 74 swine farm owners, employees, their family members, and veterinarians in rural south-central Wisconsin, compared with 114 urban Milwaukee, Wisconsin, residents. The number of swine farm participants with positive serum hemagglutination-inhibition (HI) antibody titers >40 to swine influenza viruses (17/74) was significantly higher (p<0.001) than the number of seropositive urban control samples (1/114). The geometric mean serum HI antibody titers to swine influenza viruses were also significantly higher (p<0.001) among the farm participants. Swine virus seropositivity was significantly (p<0.05) associated with being a farm owner or a farm family member, living on a farm, or entering the swine barn >4 days/week. Because pigs can play a role in generating genetically novel influenza viruses, swine farmers may represent an important sentinel population to evaluate the emergence of new pandemic influenza viruses. KW - swine KW - influenza KW - zoonosis KW - seroprevalence KW - H1 KW - hemagglutination-inhibition KW - United States DO - 10.3201/eid0808.010474 UR - https://wwwnc.cdc.gov/eid/article/8/8/01-0474_article ER - End of Reference