Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 8, Number 8—August 2002
Commentary

Nature of the Virus Associated with Endemic Balkan Nephropathy

Cristina Riquelme*, David Escors*, Javier Ortego*, Carlos M. Sanchez*, Branislava Uzelac-Keserovic†, Konstantin Apostolov‡, and Luis Enjuanes*Comments to Author 
Author affiliations: *Campus Universidad Autónoma, Cantoblanco, Madrid, Spain; †Institute of Virology “Torlak,” Belgrade, Yugoslavia; ‡Royal Postgraduate Medical School, London, United Kingdom;

Main Article

Figure

Electron microscopy images of thin sections and partially purified virions from cells infected with coronavirus or a virus tentatively associated with the endemic Balkan nephropathy (EBN). A and B. Electron microscopy images of thin sections of swine testicle cell infected with porcine transmissible gastroenteritis coronavirus (TGEV), showing virus binding to cell membrane at 8 h postinfection (A) or immature TGEV virions in the Golgi cisternae (C). B and D. Micrographs of thin sections of Vero cells infected with the virus tentatively associated with EBN at 12 h postinfection. B. The presence of EBN virions in the cytoplasm of the infected cells is indicated by arrows. D. Disorganization of the cytoplasmic membranous system in EBN-infected Vero cells. Electron microscopy images of concentrated TGEV (E) or EBN (F) virions negatively stained with 2% uranyl acetate. Bars in panels A–F represent 50 nm.

Figure. Electron microscopy images of thin sections and partially purified virions from cells infected with coronavirus or a virus tentatively associated with the endemic Balkan nephropathy (EBN). A and B. Electron microscopy images of thin sections of swine testicle cell infected with porcine transmissible gastroenteritis coronavirus (TGEV), showing virus binding to cell membrane at 8 h postinfection (A) or immature TGEV virions in the Golgi cisternae (C). B and D. Micrographs of thin sections of Vero cells infected with the virus tentatively associated with EBN at 12 h postinfection. B. The presence of EBN virions in the cytoplasm of the infected cells is indicated by arrows. D. Disorganization of the cytoplasmic membranous system in EBN-infected Vero cells. Electron microscopy images of concentrated TGEV (E) or EBN (F) virions negatively stained with 2% uranyl acetate. Bars in panels A–F represent 50 nm.

Main Article

Page created: July 16, 2010
Page updated: July 16, 2010
Page reviewed: July 16, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external