Volume 8, Number 8—August 2002
Commentary
Nature of the Virus Associated with Endemic Balkan Nephropathy
Figure

Figure. Electron microscopy images of thin sections and partially purified virions from cells infected with coronavirus or a virus tentatively associated with the endemic Balkan nephropathy (EBN). A and B. Electron microscopy images of thin sections of swine testicle cell infected with porcine transmissible gastroenteritis coronavirus (TGEV), showing virus binding to cell membrane at 8 h postinfection (A) or immature TGEV virions in the Golgi cisternae (C). B and D. Micrographs of thin sections of Vero cells infected with the virus tentatively associated with EBN at 12 h postinfection. B. The presence of EBN virions in the cytoplasm of the infected cells is indicated by arrows. D. Disorganization of the cytoplasmic membranous system in EBN-infected Vero cells. Electron microscopy images of concentrated TGEV (E) or EBN (F) virions negatively stained with 2% uranyl acetate. Bars in panels A–F represent 50 nm.