TY - JOUR AU - Gillespie, Iain AU - O’Brien, Sarah J. AU - Frost, Jennifer A. AU - Adak, Goutam K. AU - Phong, Le Hong AU - Swan, Anthony V. AU - Painter, Michael J. AU - Neal, Keith R. T1 - A Case-Case Comparison of Campylobacter coli and Campylobacter jejuni Infection: A Tool for Generating Hypotheses T2 - Emerging Infectious Disease journal PY - 2002 VL - 8 IS - 9 SP - 937 SN - 1080-6059 AB - Preventing campylobacteriosis depends on a thorough understanding of its epidemiology. We used case-case analysis to compare cases of Campylobacter coli infection with cases of C. jejuni infection, to generate hypotheses for infection from standardized, population-based sentinel surveillance information in England and Wales. Persons with C. coli infection were more likely to have drunk bottled water than were those with C. jejuni infection and, in general, were more likely to have eaten pâté. Important differences in exposures were identified for these two Campylobacter species. Exposures that are a risk for infection for both comparison groups might not be identified or might be underestimated by case-case analysis. Similarly, the magnitude or direction of population risk cannot be assessed accurately. Nevertheless, our findings suggest that case-control studies should be conducted at the species level. KW - Campylobacter KW - epidemiology KW - surveillance KW - hypothesis generation KW - risk KW - United Kingdom DO - 10.3201/eid0809.010187 UR - https://wwwnc.cdc.gov/eid/article/8/9/01-0187_article ER - End of Reference