TY - JOUR AU - Shmuely, Haim AU - Obure, Samson AU - Passaro, Douglas J. AU - Abuksis, Galia AU - Yahav, Jacob AU - Fraser, Gerald AU - Pitlik, Silvio AU - Niv, Yaron T1 - Dyspepsia Symptoms and Helicobacter pylori Infection, Nakuru, Kenya T2 - Emerging Infectious Disease journal PY - 2003 VL - 9 IS - 9 SP - 1103 SN - 1080-6059 AB - The prevalence of Helicobacter pylori infection was studied in 138 patients with dyspepsia in a hospital in Nakuru, Kenya, and in 138 asymptomatic sex- and age-matched controls from the same population. Anti–H. pylori immunoglobulin (Ig) G was more prevalent in dyspeptic than asymptomatic persons (71% vs. 51%), particularly those <30 years old (71% vs. 38%). H. pylori seropositivity was associated with dyspepsia after adjusting for age, sex, and residence (urban or rural). Among adults, the association between H. pylori infection and dyspepsia remained after adjusting for the above factors and for educational attainment, family size, and manual occupation. H. pylori infection in asymptomatic residents of Nakuru, Kenya, was more prevalent in older persons, with a rate of 68%, than in those 31–40 years of age. However, young persons with dyspepsia had an unexpectedly high prevalence of H. pylori infection. H. pylori test-and-treat strategy should be considered in Kenyan patients with dyspepsia, particularly in persons <30 years of age. KW - Helicobacter pylori KW - dyspepsia KW - Kenya KW - Africa DO - 10.3201/eid0909.020374 UR - https://wwwnc.cdc.gov/eid/article/9/9/02-0374_article ER - End of Reference