TY - JOUR AU - Van Beneden, Chris A. AU - Lexau, Catherine AU - Baughman, Wendy AU - Barnes, Brenda AU - Bennett, Nancy AU - Cassidy, P. Maureen AU - Pass, Margaret AU - Gelling, Lisa AU - Barrett, Nancy L. AU - Zell, Elizabeth R. AU - Whitney, Cynthia G. T1 - Aggregated Antibiograms and Monitoring of Drug-Resistant Streptococcus pneumoniae T2 - Emerging Infectious Disease journal PY - 2003 VL - 9 IS - 9 SP - 1089 SN - 1080-6059 AB - Community-specific antimicrobial susceptibility data may help monitor trends among drug-resistant Streptococcus pneumoniae and guide empiric therapy. Because active, population-based surveillance for invasive pneumococcal disease is accurate but resource intensive, we compared the proportion of penicillin-nonsusceptible isolates obtained from existing antibiograms, a less expensive system, to that obtained from 1 year of active surveillance for Georgia, Tennessee, California, Minnesota, Oregon, Maryland, Connecticut, and New York. For all sites, proportions of penicillin-nonsusceptible isolates from antibiograms were within 10 percentage points (median 3.65) of those from invasive-only isolates obtained through active surveillance. Only 23% of antibiograms distinguished between isolates intermediate and resistant to penicillin; 63% and 57% included susceptibility results for erythromycin and extended-spectrum cephalosporins, respectively. Aggregating existing hospital antibiograms is a simple and relatively accurate way to estimate local prevalence of penicillin-nonsusceptible pneumococcus; however, antibiograms offer limited data on isolates with intermediate and high-level penicillin resistance and isolates resistant to other agents. KW - Streptococcus pneumoniae KW - antibiogram KW - pneumococcal infections KW - drug resistance KW - population surveillance KW - epidemiology KW - United States DO - 10.3201/eid0909.020620 UR - https://wwwnc.cdc.gov/eid/article/9/9/02-0620_article ER - End of Reference