Vaccine-Preventable Diseases: Bacterial

CDC Yellow Book 2024

Travel-Associated Infections & Diseases

Table 5-01: Vaccine-Preventable Diseases: Bacterial

VACCINE TRADE NAME (MANUFACTURER) DESCRIPTION1 & ROUTE OF ADMINISTRATION AGE LIMITS DOSES PRESCRIBING & BOOSTER INFORMATION, RECOMMENDATIONS & RESTRICTIONS

Anthrax

BioThrax (Emergent BioSolutions)

Cell-free filtrates of avirulent Bacillus anthracis, IM or SC (SC preferred)

18–65 y

3

Biothrax
Anthrax ACIP Vaccine Recommendations

Cholera

VAXCHORA (Emergent BioSolutions)

Live-attenuated, PO

50 mL
2 to <6 y

1

VAXCHORA
Cholera ACIP Vaccine Recommendations

100 mL
≥26–64 y

1

Diphtheria

For all diphtheria vaccines licensed for use in the United States, see: Vaccines Licensed for Use in the United States

Diphtheria

Adacel (TDaP) (Sanofi Pasteur)

Tetanus, diphtheria toxoids + acellular pertussis antigens, IM

10–64 y

1

Adacel DTaP/Tdap/Td ACIP Vaccine Recommendations

Diphtheria

BOOSTRIX (TDaP) (GlaxoSmithKline)

Tetanus, diphtheria toxoids + pertussis antigens, IM

≥10 y

1

Boostrix
DTaP/Tdap/Td ACIP Vaccine Recommendations

Diphtheria

TDVAX (MassBiologics)

Tetanus, diphtheria toxoids, IM

≥7 y

3 (primary series) + 1 (booster)

TDVAX
DTaP/Tdap/Td ACIP Vaccine Recommendations

Diphtheria

TENIVAC (Td) (Sanofi Pasteur)

Tetanus, diphtheria toxoids, IM

≥7 y

3 (primary series) + 1 (booster)

TENIVAC
DTaP/Tdap/Td ACIP Vaccine Recommendations

Meningococcal (Quadrivalent, ACWY)

Menactra (Sanofi Pasteur)

Conjugate, IM

9–23 mo

2

Menactra Meningococcal ACIP Vaccine Recommendations

≥2 y

1

Meningococcal (Quadrivalent, ACWY)

MenQuadfi (Sanofi Pasteur)

Conjugate, IM

≥2 y

1

MenQuadfi
Meningococcal ACIP Vaccine Recommendations

Meningococcal (Quadrivalent, ACWY)

MENVEO (GlaxoSmithKline)

Conjugate, IM

2 mo

4

MENVEO
Meningococcal ACIP Vaccine Recommendations

Meningococcal (Quadrivalent, ACWY)

3–6 mo

Depends on age at 1st vaccination

Meningococcal (Quadrivalent, ACWY)

7–23 mo

2

Meningococcal (Quadrivalent, ACWY)

≥2 y

1

Meningococcal (Monovalent, B)

BEXSERO (GlaxoSmithKline)

Recombinant, IM

10–25 y

2

BEXSERO
Meningococcal ACIP Vaccine Recommendations

Meningococcal (Monovalent, B)

TRUMENBA (Pfizer)

Recombinant, IM

10–25 y

2

TRUMENBA
Meningococcal ACIP Vaccine Recommendations

Pertussis For all pertussis vaccines licensed for use in the United States, see: Vaccines Licensed for Use in the United States

Pertussis

Adacel (TDaP) (Sanofi Pasteur)

Tetanus, diphtheria toxoids + acellular pertussis antigens, IM

10–64 y

1

Adacel
DTaP/Tdap/Td ACIP Vaccine Recommendations

Pertussis

BOOSTRIX (TDaP) (GlaxoSmithKline)

Tetanus, diphtheria toxoids + pertussis antigens, IM

≥10 y

1

Boostrix
DTaP/Tdap/Td ACIP Vaccine Recommendations

Plague Discontinued in 1999; newer vaccines in development, none commercially available or FDA-approved

Pneumococcal

PREVNAR 13 (Wyeth)

Conjugate, IM

6 wk to <6 y

4

Prevnar 13
Pneumococcal ACIP Vaccine Recommendations

Pneumococcal

6 y to <18 y

1

Pneumococcal

VAXNEUVANCE (Merck)

Conjugate, IM

≥18 y

1

VAXNEUVANCE
Pneumococcal ACIP Vaccine Recommendations

Pneumococcal

PREVNAR 20 (Wyeth)

Conjugate, IM

≥18 y

1

PREVNAR 20
Pneumococcal ACIP Vaccine Recommendations

Pneumococcal

PNEUMOVAX 23 (Merck)

Polysaccharide, IM or SC

≥50 y

1

PNEUMOVAX 23 - Pneumococcal Vaccine, Polyvalent
Pneumococcal ACIP Vaccine Recommendations

Q fever Available in Australia only
Tetanus For all tetanus vaccines licensed for use in the United States, see: Vaccines Licensed for Use in the United States

Tetanus

Adacel (TDaP) (Sanofi Pasteur)

Tetanus, diphtheria toxoids + acellular pertussis antigens, IM

10–64 y

1

Adacel
DTaP/Tdap/Td ACIP Vaccine Recommendations

Tetanus

BOOSTRIX (TDaP) (GlaxoSmithKline)

Tetanus, diphtheria toxoids + pertussis antigens, IM

≥10 y

1

Boostrix
DTaP/Tdap/Td ACIP Vaccine Recommendations

Tetanus

TDVAX (MassBiologics)

Tetanus, diphtheria toxoids, IM

≥7 y

3 (primary series) + 1 (booster)

TDVAX
DTaP/Tdap/Td ACIP Vaccine Recommendations

Tetanus

TENIVAC (Td) (Sanofi Pasteur)

Tetanus, diphtheria toxoids, IM

≥7 y

3 (primary series) + 1 (booster)

TENIVAC
DTaP/Tdap/Td ACIP Vaccine Recommendations

Tuberculosis bacillus Calmette-Guérin (BCG) is no longer commercially available in the United States

Typhoid fever

Typhim Vi (Sanofi Pasteur)

Polysaccharide, IM

≥2 y

1

Typhim Vi
Typhoid ACIP Vaccine Recommendations

Typhoid fever

Vivotif (Emergent BioSolutions)

Live-attenuated, PO

≥6 y

4

Vivotif [PDF]
Typhoid ACIP Vaccine Recommendations

Abbreviations: IM, intramuscular; PO, orally; SC, subcutaneously
1For an overview and description of vaccine types, see: www.hhs.gov/immunization/basics/types/index.html