Vaccine-Preventable Diseases: Viral

CDC Yellow Book 2024

Travel-Associated Infections & Diseases

Table 5-08 Vaccine-Preventable Diseases: Viral

VACCINE

TRADE NAME (MANUFACTURER)

DESCRIPTION1 & ROUTE OF ADMINISTRATION

AGE LIMITS

DOSES

PRESCRIBING & BOOSTER INFORMATION, RECOMMENDATIONS & RESTRICTIONS

COVID-19

COMIRNATY (Pfizer-BioNTech)

mRNA, IM

≥6 months

Stay Up to Date with COVID-19 Vaccines

COVID-19

SPIKEVAX (Moderna)

mRNA, IM

≥6 months

Stay Up to Date with COVID-19 Vaccines

COVID-19

NOVAVAX (Novavax)

Recombinant, IM

≥12 years

Stay Up to Date with COVID-19 Vaccines

Dengue

DENGVAXIA (Sanofi Pasteur)

Live-attenuated, SC

9–16 y

3

Restrictions apply DENGVAXIA
Dengue ACIP Vaccine Recommendations

Ebola Zaire

ERVEBO (Merck)

Live-attenuated, IM

≥18 y

1

Restrictions apply
ERVEBO
Ebola Vaccine: Information about ERVEBO®

Enterovirus-A71 (Hand, Foot & Mouth)

Available in China only

Hepatitis A

HAVRIX (GlaxoSmithKline)

Inactivated, IM

0.5 mL

HAVRIX
Hepatitis A ACIP Vaccine Recommendations

≥12 mo to <19 y

2

Hepatitis A

HAVRIX (GlaxoSmithKline)

Inactivated, IM

1.0 mL

HAVRIX
Hepatitis A ACIP Vaccine Recommendations

≥19 y

2

Hepatitis A

VAQTA (Merck)

Inactivated, IM

0.5 mL

VAQTA
Hepatitis A ACIP Vaccine Recommendations

≥12 mo to <19 y

2

Hepatitis A

VAQTA (Merck)

Inactivated, IM

1.0 mL

VAQTA
Hepatitis A ACIP Vaccine Recommendations

≥19 y

2

Hepatitis A + Hepatitis B

TWINRIX (GlaxoSmithKline)

Inactivated HAV + Recombinant HBV, IM

STANDARD DOSING

TWINRIX
Hepatitis A ACIP Vaccine Recommendations

≥18 y

3

Hepatitis A + Hepatitis B

TWINRIX (GlaxoSmithKline)

Inactivated HAV + Recombinant HBV, IM

ACCELERATED DOSING

TWINRIX
Hepatitis A ACIP Vaccine Recommendations

≥18 y

3 (+ booster)

Hepatitis B

ENGERIX-B (GlaxoSmithKline)

Recombinant, IM

<20 y

3

ENGERIX-B
Hepatitis B ACIP Vaccine Recommendations

≥20 y

3

Hepatitis B

HEPLISAV-B (Dynavax Technologies)

Recombinant, IM

≥18 y

2

HEPLISAV-B
Hepatitis B ACIP Vaccine Recommendations

Hepatitis B

PREHEVBRIO (VBI Vaccines)

Recombinant, IM

≥18 y

3

PREHEVBRIO
Hepatitis B ACIP Vaccine Recommendations

Hepatitis B

RECOMBIVAX HB (Merck)

Recombinant, IM

Less than 20 y

3

Recombivax HB
Hepatitis B ACIP Vaccine Recommendations

Influenza

For the list of influenza vaccines licensed for use in the United States, see: Vaccines Licensed for Use in the United States
Influenza ACIP Vaccine Recommendations

Japanese encephalitis

IXIARO (Valneva)

Inactivated, IM

0.25 mL

IXIARO
Japanese Encephalitis ACIP Vaccine Recommendations

≥2 mo to <3 y

2

Japanese encephalitis

IXIARO (Valneva)

Inactivated, IM

0.5 mL

IXIARO
Japanese Encephalitis ACIP Vaccine Recommendations

≥3 y

2

Mumps

M-M-R II (Merck)

Live-attenuated, SC

<12 mo

3

Measles, Mumps and Rubella Virus Vaccine Live
MMR ACIP Vaccine Recommendations (Measles, Mumps and Rubella)

≥12 mo

2

Mumps

ProQuad (Merck)

Live-attenuated, SC

≥12 mo to <13 y

2

PROQUAD
MMRV ACIP Vaccine Recommendations (Measles, Mumps, Rubella, and Varicella)

Polio

IPOL (Sanofi Pasteur)

Inactivated, IM or SC

CHILDREN

IPOL - Poliovirus Vaccine Inactivated (Monkey Kidney Cell)
Polio ACIP Vaccine Recommendations
Polio: For Travelers

≥6 wks

3

ADULTS TRAVELING TO AREAS WITH INCREASED RISK OF POLIO

UNVACCINATED, PARTLY VACCINATED, VACCINATION STATUS UNKNOWN

≥18 y

3

COMPLETELY VACCINATED

≥18 y

1-time booster

Rabies

IMOVAX (Sanofi Pasteur)

Inactivated (human diploid cell), IM

all ages

2–3

IMOVAX
Rabies ACIP Vaccine Recommendations

Rabies

RabAvert (Novartis)

Inactivated (purified chick embryo cell), IM

all ages

2–3

RabAvert - Rabies Vaccine
Rabies ACIP Vaccine Recommendations

Rubella

M-M-R II (Merck)

Live-attenuated, SC

<12 mo

3

Measles, Mumps and Rubella Virus Vaccine Live
MMR ACIP Vaccine Recommendations (Measles, Mumps and Rubella)

≥12 mo

2

Rubella

ProQuad (Merck)

Live-attenuated, SC

≥12 mo to <13 y

2

PROQUAD
MMRV ACIP Vaccine Recommendations (Measles, Mumps, Rubella, and Varicella)

Rubeola / Measles

M-M-R II (Merck)

Live-attenuated, SC

<12 mo

3

Measles, Mumps and Rubella Virus Vaccine Live
MMR ACIP Vaccine Recommendations (Measles, Mumps and Rubella)

≥12 mo

2

Rubeola / Measles

ProQuad (Merck)

Live-attenuated, SC

≥12 mo to <13 y

2

PROQUAD
MMRV ACIP Vaccine Recommendations (Measles, Mumps, Rubella, and Varicella)

Tick-borne encephalitis

TICOVAC (Pfizer)

Inactivated, IM

0.25 mL

TICOVAC

≥1–15 y

3

Tick-borne encephalitis

TICOVAC (Pfizer)

Inactivated, IM

0.5 mL

TICOVAC

≥16 y

3

Varicella / Chickenpox

VARIVAX (Merck)

Live-attenuated, SC

1–12 y

2

VARIVAX (refrigerated and frozen formulations)
Varicella Vaccination Information for Healthcare Professionals

≥ 13 y

2

Varicella / Chickenpox

ProQuad (Merck)

Live-attenuated, SC

≥12 mo to <13 y

2

PROQUAD
MMRV ACIP Vaccine Recommendations (Measles, Mumps, Rubella, and Varicella)

Variola / Smallpox + Mpox

ACAM2000 (Emergent BioSolutions)

Live-attenuated vaccinia virus, percutaneous via bifurcated needle

all ages

1

Restrictions apply  ACAM2000
Orthopoxviruses (Smallpox and Monkeypox) ACIP Vaccine Recommendations

Variola / Smallpox + Mpox

JYNNEOS (Bavarian Nordic)

Live-attenuated non-replicating vaccinia virus, SC

≥18 y

2

Restrictions apply  JYNNEOS
Orthopoxviruses (Smallpox and Monkeypox) ACIP Vaccine Recommendations

Yellow Fever

YF-VAX (Sanofi Pasteur)

Live-attenuated, SC

≥9 mo

1

YF-Vax
Yellow Fever ACIP Vaccine Recommendations

Abbreviations: IM, intramuscular; SC, subcutaneously

1For an overview and description of vaccine types, see: www.hhs.gov/immunization/basics/types/index.html