Volume 10, Number 1—January 2004
Research
Fluoroquinolones Protective against Cephalosporin Resistance in Gram-negative Nosocomial Pathogens
Table 2
Multivariable analysis of outcomea
| Characteristic | HR (95% CI)b | p |
|---|---|---|
| Surgery during risk period | 1.62 (1.16 to 2.25) | 0.005 |
| In intensive care unit during risk period | 2.17 (1.49 to 3.16) | <0.001 |
| Receipt of β-lactam/β-lactamase inhibitor | 2.52 (1.67 to 3.80) | <0.001 |
| Receipt of ureidopenicillin | 2.55 (1.43 to 4.53) | 0.002 |
| Receipt of 3rd-generation cephalosporin | 2.84 (1.89 to 4.27) | <0.001 |
| Receipt of fluoroquinolone | 0.40 (0.21 to 0.76) | 0.005 |
aOutcome refers to the isolation of third-generation cephalosporin-resistant Enterobacter spp., Pseudomonas aeruginosa, or Klebsiella pneumoniae from a clinical specimen.
bHR, hazard ratio; CI, confidence interval.
