Fungal Diseases Spotlight

Worldwide, more than one billion people get a fungal infection each year.

Although there are anywhere from 1 to 5 million species of fungi, only a few hundred possess pathogenic traits. The most common fungal infections are ringworm and vaginal yeast infections.

Fungal infections range from mild to life-threatening, putting people with weakened immune systems at risk for the most fungal infections. Fungal disease outbreaks are rare, and some have occurred following extreme weather events. There are only a few types of antifungal medicines. Increasingly, fungi are becoming resistant to one or more medicines.

2024

Current Issue Clinical Manifestations, Antifungal Drug Susceptibility, and Treatment Outcomes for Emerging Zoonotic Cutaneous Sporotrichosis, Thailand
Pattriya Jirawattanadon et al. Volume 30, Number 12—December 2024 Current Issue Autochthonous Blastomyces dermatitidis, India
Anuradha Chowdhary et al. Volume 30, Number 12—December 2024 Suspected Acute Pulmonary Coccidioidomycosis in Traveler Returning to Switzerland from Peru
Andreas Neumayr et al. Volume 30, Number 11—November 2024 Recognition of Antifungal-Resistant Dermatophytosis by Infectious Diseases Specialists, United States
Jeremy A.W. Gold et al. Volume 30, Number 9—September 2024 Systematic Review of Prevalence of Histoplasma Antigenuria in Persons with HIV in Latin America and Africa
Preethiya Sekar et al. Volume 30, Number 8—August 2024 Molecular Identification of Fonsecaea monophora, Novel Agent of Fungal Brain Abscess
Sudesh Gourav et al. Volume 30, Number 6—June 2024 Paranannizziopsis spp. Infection in Wild Vipers, Europe
Gaëlle Blanvillain et al. Volume 30, Number 5—May 2024 Sporotrichosis Cluster in Domestic Cats and Veterinary Technician, Kansas, USA, 2022
Ian Hennessee et al. Volume 30, Number 5—May 2024 Potential Sexual Transmission of Antifungal-Resistant Trichophyton indotineae
Stephanie Spivack et al. Volume 30, Number 4—April 2024

2023

Human Lobomycosis Caused by Paracoccidioides (Lacazia) loboi, Panama, 2022
Jose A. Suárez et al. Volume 29, Number 12—December 2023 Etymologia: Lacazia loboi
W. Clyde Partin Volume 29, Number 12—December 2023 Case Report and Literature Review of Prosthetic Cardiovascular Mucormycosis
Baptiste Hoellinger et al. Volume 29, Number 11—November 2023 Scedosporium Infection in Recipients of Kidney Transplants from Deceased Near-Drowning Donor
Devprakash Choudhary et al. Volume 29, Number 11—November 2023 Candida auris Clinical Isolates Associated with Outbreak in Neonatal Unit of Tertiary Academic Hospital, South Africa
Dikeledi Kekana et al. Volume 29, Number 10—October 2023 High Prevalence of Candida auris Colonization during Protracted Neonatal Unit Outbreak, South Africa
Liliwe Shuping et al. Volume 29, Number 9—September 2023 Nationwide Outbreak of Candida auris Infections Driven by COVID-19 Hospitalizations, Israel, 2021–2022
Roni Biran et al. Volume 29, Number 7—July 2023 Candida auris‒Associated Hospitalizations, United States, 2017–2022
Kaitlin Benedict et al. Volume 29, Number 7—July 2023 Clinical and Mycologic Characteristics of Emerging Mucormycosis Agent Rhizopus homothallicus
Shivaprakash M. Rudramurthy et al. Volume 29, Number 7—July 2023 Increased Hospitalizations Involving Fungal Infections during COVID-19 Pandemic, United States, January 2020–December 2021
Jeremy A.W. Gold et al. Volume 29, Number 7—July 2023 Multicentric Case Series and Literature Review of Coccidioidal Otomastoiditis
Ilan S. Schwartz et al. Volume 29, Number 7—July 2023 Etymologia: Fonsecaea pedrosoi
Dayane Moraes et al. Volume 29, Number 7—July 2023 “On the Bat’s Back I Do Fly after Summer Merrily”
Byron Breedlove Volume 29, Number 7—July 2023 Candida vulturna Outbreak Caused by Cluster of Multidrug-Resistant Strains, China
Han Du et al. Volume 29, Number 7—July 2023 Nannizzia polymorpha as Rare Cause of Skin Dermatophytosis
Pei-Lun Sun et al. Volume 29, Number 7—July 2023 Clonal Dissemination of Antifungal-Resistant Candida haemulonii, China
Xinfei Chen et al. Volume 29, Number 3—March 2023 Emergomyces pasteurianus in Man Returning to the United States from Liberia and Review of the Literature
Jacob Pierce et al. Volume 29, Number 3—March 2023

2022

Podcast Ophidiomyces ophiodiicola, Etiologic Agent of Snake Fungal Disease, in Europe since Late 1950s
Francesco C. Origgi et al. Volume 28, Number 10—October 2022 Listen to the podcast Endofungal Mycetohabitans rhizoxinica Bacteremia Associated with Rhizopus microsporus Respiratory Tract Infection
Shangxin Yang et al. Volume 28, Number 10—October 2022 Podcast Fatal Fungicide-Associated Triazole-Resistant Aspergillus fumigatus Infection, Pennsylvania, USA
Kennedy Bradley et al. Volume 28, Number 9—September 2022 Listen to the podcast Rigidoporus corticola Colonization and Invasive Fungal Disease in Immunocompromised Patients, United States
Alvaro C. Laga et al. Volume 28, Number 4—April 2022 Outbreak of Mucormycosis in Coronavirus Disease Patients, Pune, India
Samir Joshi et al. Volume 28, Number 1—January 2022 Fungal Infections Caused by Kazachstania spp., Strasbourg, France, 2007–2020
Charlotte Kaeuffer et al. Volume 28, Number 1—January 2022 Emergence of Difficult-to-Treat Tinea Corporis Caused by Trichophyton mentagrophytes Complex Isolates, Paris, France
Sarah Dellière et al. Volume 28, Number 1—January 2022

2021

Online Registry of COVID-19–Associated Mucormycosis Cases, India, 2021
Shitij Arora et al. Volume 27, Number 11—November 2021 Etymologia: Prototheca
Rüdiger D. Ollhoff et al. Volume 27, Number 11—November 2021 Podcast Epidemiology, Clinical Features, and Outcomes of Coccidioidomycosis, Utah, 2006–2015
Adrienne Carey et al. Volume 27, Number 9—September 2021 Listen to the podcast Talaromyces marneffei
Monika Mahajan Volume 27, Number 9—September 2021 Paracoccidioides
Lucas Nojosa Oliveira et al. Volume 27, Number 9—September 2021 Podcast Considering Mycological Rarities
Byron Breedlove Volume 27, Number 9—September 2021 Listen to the podcast Fungemia and Other Fungal Infections Associated with Use of Saccharomyces boulardii Probiotic Supplements
Juha Rannikko et al. Volume 27, Number 8—August 2021 Genomic Characterizations of Clade III Lineage of Candida auris, California, USA
Travis K. Price et al. Volume 27, Number 4—April 2021 Fluconazole-Resistant Candida glabrata Bloodstream Isolates, South Korea, 2008–2018
Eun Jeong Won et al. Volume 27, Number 3—March 2021 Etymologia: Histoplasma capsulatum
Monika Mahajan Volume 27, Number 3—March 2021 Aspergillosis Complicating Severe Coronavirus Disease
Kieren A. Marr et al. Volume 27, Number 1—January 2021 Invasive Fusariosis in Nonneutropenic Patients, Spain, 2000–2015
Elena Pérez-Nadales et al. Volume 27, Number 1—January 2021

2020

Risk-Based Estimate of Human Fungal Disease Burden, China
Ling-Hong Zhou et al. Volume 26, Number 9—September 2020 Invasive Infections with Nannizziopsis obscura Species Complex in 9 Patients from West Africa, France, 2004–2020
Dea Garcia-Hermoso et al. Volume 26, Number 9—September 2020 Fatal Invasive Aspergillosis and Coronavirus Disease in an Immunocompetent Patient
Marion Blaize et al. Volume 26, Number 7—July 2020 Paradoxal Trends in Azole-Resistant Aspergillus fumigatus in a National Multicenter Surveillance Program, the Netherlands, 2013–2018
Pieter P.A. Lestrade et al. Volume 26, Number 7—July 2020 Cannabis Use and Fungal Infections in a Commercially Insured Population, United States, 2016
Kaitlin Benedict et al. Volume 26, Number 6—June 2020 Endemic Chromoblastomycosis Caused Predominantly by Fonsecaea nubica, Madagascar
Tahinamandranto Rasamoelina et al. Volume 26, Number 6—June 2020 Donor-Derived Transmission of Cryptococcus gattii sensu lato in Kidney Transplant Recipients
Daniel W.C.L. Santos et al. Volume 26, Number 6—June 2020 Blastomycosis in Minnesota, USA, 1999–2018
Malia Ireland et al. Volume 26, Number 5—May 2020 Invasive Candida bovina Infection, France
Kévin Brunet et al. Volume 26, Number 3—March 2020 High Azole Resistance in Aspergillus fumigatus Isolates from Strawberry Fields, China, 2018
Yong Chen et al. Volume 26, Number 1—January 2020

2019

A Study in Stillness and Symmetry
Byron Breedlove Volume 25, Number 10—October 2019 Disease Exposure and Antifungal Bacteria on Skin of Invasive Cane Toads, Australia
Chava L. Weitzman et al. Volume 25, Number 9—September 2019 Soft Tissue Infection with Diaporthe phaseolorum in Heart Transplant Recipient with End-Stage Renal Failure
Julia C. Howard et al. Volume 25, Number 9—September 2019 Disseminated Emergomycosis in a Person with HIV Infection, Uganda
Isabelle Rooms et al. Volume 25, Number 9—September 2019 Invasive Fungal Disease, Isavuconazole Treatment Failure, and Death in Acute Myeloid Leukemia Patients
Anne-Pauline Bellanger et al. Volume 25, Number 9—September 2019 Epidemiologic Shift in Candidemia Driven by Candida auris, South Africa, 2016–2017
Erika van Schalkwyk et al. Volume 25, Number 9—September 2019 Etymologia: Sporothrix schenckii
Fábio P. Sellera et al. Volume 25, Number 9—September 2019 Beatrix Potter, Author, Naturalist, Mycologist
Byron Breedlove Volume 25, Number 9—September 2019 Potential Fifth Clade of Candida auris, Iran, 2018
Nancy A. Chow et al. Volume 25, Number 9—September 2019 Classification of Trauma-Associated Invasive Fungal Infections to Support Wound Treatment Decisions
Anuradha Ganesan et al. Volume 25, Number 9—September 2019 Environmental Hotspots for Azole Resistance Selection of Aspergillus fumigatus, the Netherlands
Sijmen E. Schoustra et al. Volume 25, Number 7—July 2019 Lobomycosis in Soldiers, Colombia
Claudia M. Arenas et al. Volume 25, Number 4—April 2019 Malignant Aspergillus flavus Otitis Externa with Jugular Thrombosis
Maxime Moniot et al. Volume 25, Number 4—April 2019 Utility of Whole-Genome Sequencing to Ascertain Locally Acquired Cases of Coccidioidomycosis, Washington, USA
Hanna N. Oltean et al. Volume 25, Number 3—March 2019 In Vivo Selection of a Unique Tandem Repeat Mediated Azole Resistance Mechanism (TR₁₂₀) in Aspergillus fumigatus cyp51A, Denmark
Rasmus K. Hare et al. Volume 25, Number 3—March 2019 Management of Patients with Candida auris Fungemia at Community Hospital, Brooklyn, New York, USA, 2016–2018
Jenny YeiSol Park et al. Volume 25, Number 3—March 2019 Autochthonous Transmission of Coccidioides in Animals, Washington, USA
Allison E. James et al. Volume 25, Number 1—January 2019

2018

Molecular Typing and Antifungal Susceptibility of Candida viswanathii, India
Shamanth A. Shankarnarayan et al. Volume 24, Number 10—October 2018 Podcast Enhanced Surveillance for Coccidioidomycosis, 14 US States, 2016
Kaitlin Benedict et al. Volume 24, Number 8—August 2018 Listen to the podcast Recovery of Cryptococcus gattii from an Infected Ventriculo-Peritoneal Shunt, Illinois, USA
Donna Moritz et al. Volume 24, Number 7—July 2018 Large Outbreaks of Fungal and Bacterial Bloodstream Infections in a Neonatal Unit, South Africa, 2012–2016
Erika van Schalkwyk et al. Volume 24, Number 7—July 2018 Emergomyces canadensis, a Dimorphic Fungus Causing Fatal Systemic Human Disease in North America
Ilan S. Schwartz et al. Volume 24, Number 4—April 2018 Podcast Reemergence of Intravenous Drug Use as Risk Factor for Candidemia, Massachusetts, USA
Nongnooch Poowanawittayakom et al. Volume 24, Number 4—April 2018 Listen to the podcast Invasive Infections Caused by Nannizziopsis spp. Molds in Immunocompromised Patients
Céline Nourrisson et al. Volume 24, Number 3—March 2018 Emergomyces africanus in Soil, South Africa
Ilan S. Schwartz et al. Volume 24, Number 2—February 2018 Recognition of Azole-Resistant Aspergillosis by Physicians Specializing in Infectious Diseases, United States
Tiffany A. Walker et al. Volume 24, Number 1—January 2018 Inonotosis in Patient with Hematologic Malignancy
Ana Fernández-Cruz et al. Volume 24, Number 1—January 2018

2017

mcr-1 Colistin Resistance in ESBL-Producing Klebsiella pneumoniae, France
Yvan Caspar et al. Volume 23, Number 5—May 2017 Fungal Contamination of Methylprednisolone Causing Recurrent Lumbosacral Intradural Abscess
Jaclyn J. Renfrow et al. Volume 23, Number 3—March 2017 Podcast Delivering on Antimicrobial Resistance Agenda Not Possible without Improving Fungal Diagnostic Capabilities
David W. Denning et al. Volume 23, Number 2—February 2017 Listen to the podcast Fatal Emmonsia sp. Infection and Fungemia after Orthotopic Liver Transplantation
Shanthi Kappagoda et al. Volume 23, Number 2—February 2017 Etymologia: Emmonsia
Ronnie Henry Volume 23, Number 2—February 2017 Biofilm-Forming Capability of Highly Virulent, Multidrug-Resistant Candida auris
Leighann Sherry et al. Volume 23, Number 2—February 2017 Epidemiology of Hospitalizations Associated with Invasive Candidiasis, United States, 2002–2012
Sara Strollo et al. Volume 23, Number 1—January 2017

2016

Red Fox as Sentinel for Blastomyces dermatitidis, Ontario, Canada
Nicole M. Nemeth et al. Volume 22, Number 7—July 2016 Etymologia: Batrachochytrium salamandrivorans
Volume 22, Number 7—July 2016 Microbial Biofilms, Second Edition
Rodney M. Donlan Volume 22, Number 6—June 2016 Whole-Genome Sequencing to Determine Origin of Multinational Outbreak of Sarocladium kiliense Bloodstream Infections
Kizee A. Etienne et al. Volume 22, Number 3—March 2016 Candida haemulonii Complex Species, Brazil, January 2010–March 2015
João Nobrega de Almeida et al. Volume 22, Number 3—March 2016 Widespread Bat White-Nose Syndrome Fungus, Northeastern China
Joseph R. Hoyt et al. Volume 22, Number 1—January 2016 Multiple Fungicide-Driven Alterations in Azole-Resistant Aspergillus fumigatus, Colombia, 2015
Patrice Le Pape et al. Volume 22, Number 1—January 2016 Azole Resistance of Aspergillus fumigatus in Immunocompromised Patients with Invasive Aspergillosis
Jan W.M. van der Linden et al. Volume 22, Number 1—January 2016

2015

Mycotic Infections Acquired outside Areas of Known Endemicity, United States
Kaitlin Benedict et al. Volume 21, Number 11—November 2015 Characteristics and Factors Associated with Death among Patients Hospitalized for Severe Fever with Thrombocytopenia Syndrome, South Korea, 2013
Jaeseung Shin et al. Volume 21, Number 10—October 2015 Invasion Dynamics of White-Nose Syndrome Fungus, Midwestern United States, 2012–2014
Kate E. Langwig et al. Volume 21, Number 6—June 2015 Estimated Deaths and Illnesses Averted During Fungal Meningitis Outbreak Associated with Contaminated Steroid Injections, United States, 2012–2013
Rachel Smith et al. Volume 21, Number 6—June 2015 Lagenidium giganteum Pathogenicity in Mammals
Raquel Vilela et al. Volume 21, Number 2—February 2015 Podcast Rates and Risk Factors for Coccidioidomycosis among Prison Inmates, California, USA, 2011
Charlotte Wheeler et al. Volume 21, Number 1—January 2015 Listen to the podcast

2014

HIV-Associated Disseminated Emmonsiosis, Johannesburg, South Africa
Wesley G. van Hougenhouck-Tulleken et al. Volume 20, Number 12—December 2014 Drug-Resistant Candida glabrata Infection in Cancer Patients
Dimitrios Farmakiotis et al. Volume 20, Number 11—November 2014 Passive Surveillance for Azole-Resistant Aspergillus fumigatus, United States, 2011–2013
Cau D. Pham et al. Volume 20, Number 9—September 2014 Distance from Construction Site and Risk for Coccidioidomycosis, Arizona, USA
Janis E. Blair et al. Volume 20, Number 9—September 2014 Candida auris–Associated Candidemia, South Africa
Rindidzani E. Magobo et al. Volume 20, Number 7—July 2014 Characteristics of Patients with Mild to Moderate Primary Pulmonary Coccidioidomycosis
Janis E. Blair et al. Volume 20, Number 6—June 2014 Invasive Fungal Infections after Natural Disasters
Kaitlin Benedict et al. Volume 20, Number 3—March 2014 Fungal Endophthalmitis Associated with Compounded Products
Christina A. Mikosz et al. Volume 20, Number 2—February 2014

2013

Podcast Think Fungus—Prevention and Control of Fungal Infections
Mary E. Brandt et al. Volume 19, Number 10—October 2013 Listen to the podcast Podcast Coccidioidomycosis-associated Hospitalizations, California, USA, 2000–2011
Gail Sondermeyer et al. Volume 19, Number 10—October 2013 Listen to the podcast Cryptococcus gattii Infections in Multiple States Outside the US Pacific Northwest
Julie R. Harris et al. Volume 19, Number 10—October 2013 New Clonal Strain of Candida auris, Delhi, India
Anuradha Chowdhary et al. Volume 19, Number 10—October 2013 Pneumocystis jirovecii Genotype Associated with Increased Death Rate of HIV-infected Patients with Pneumonia
Meja Rabodonirina et al. Volume 19, Number 1—January 2013

2012

Carpal Tunnel Syndrome with Paracoccidioidomycosis
Felipe von Glehn et al. Volume 18, Number 8—August 2012 Fundamental Medical Mycology
Thomas G. Mitchell Volume 18, Number 8—August 2012 Recognition and Diagnosis of Cryptococcus gattii Infections in the United States
Sally Ann Iverson et al. Volume 18, Number 6—June 2012 Clonal Spread of Geomyces destructans among Bats, Midwestern and Southern United States
Ping Ren et al. Volume 18, Number 5—May 2012 Coccidioides posadasii Infection in Bats, Brazil
Rossana de Aguiar Cordeiro et al. Volume 18, Number 4—April 2012 Geographic Distribution of Endemic Fungal Infections among Older Persons, United States
Dirk Haselow et al. Volume 18, Number 2—February 2012 Emergence of Blastoschizomyces capitatus Yeast Infections, Central Europe
Tanja Birrenbach et al. Volume 18, Number 1—January 2012

2011

Chrysosporium sp. Infection in Eastern Massasauga Rattlesnakes
Matthew C. Allender et al. Volume 17, Number 12—December 2011 Clinical Implications of Azole Resistance in Aspergillus fumigatus, the Netherlands, 2007–2009
Jan W.M. van der Linden et al. Volume 17, Number 10—October 2011 Much have I travel’d in the realms of gold
Polyxeni Potter Volume 17, Number 10—October 2011 Tubulinosema sp. Microsporidian Myositis in Immunosuppressed Patient
Maria M. Choudhary et al. Volume 17, Number 9—September 2011 Clonal Genotype of Geomyces destructans among Bats with White Nose Syndrome, New York, USA
Sunanda S. Rajkumar et al. Volume 17, Number 7—July 2011 Common Reservoirs for Penicillium marneffei Infection in Humans and Rodents, China
Cunwei Cao et al. Volume 17, Number 2—February 2011

2010

Enhanced Surveillance of Coccidioidomycosis, Arizona, USA, 2007–2008
Clarisse A. Tsang et al. Volume 16, Number 11—November 2010 Increasing Incidence of Mucormycosis in University Hospital, Belgium
Veroniek Saegeman et al. Volume 16, Number 9—September 2010 Projecting Global Occurrence of Cryptococcus gattii
Deborah J. Springer et al. Volume 16, Number 1—January 2010

2009

Healthcare Worker Occupation and Immune Response to Pneumocystis jirovecii
Renuka Tipirneni et al. Volume 15, Number 10—October 2009 Frequency and Evolution of Azole Resistance in Aspergillus fumigatus Associated with Treatment Failure
Susan J. Howard et al. Volume 15, Number 7—July 2009

2008

Clonal Population of Flucytosine-Resistant Candida tropicalis from Blood Cultures, Paris, France
Marie Desnos-Ollivier et al. Volume 14, Number 4—April 2008 Saksenaea vasiformis Infection, French Guiana
Denis Blanchet et al. Volume 14, Number 2—February 2008

2007

Literature Review and Case Histories of Histoplasma capsulatum var. duboisii Infections in HIV-infected Patients
Pierre Loulergue et al. Volume 13, Number 11—November 2007

2006

Antimicrobial Drugs in the Home, United Kingdom
Cliodna A.M. McNulty et al. Volume 12, Number 10—October 2006 Molecular Principles of Fungal Pathogenesis
Errol Reiss Volume 12, Number 10—October 2006 Human and Canine Pulmonary Blastomycosis, North Carolina, 2001–2002
Pia D.M. MacDonald et al. Volume 12, Number 8—August 2006 Aspergillus ustus Infections among Transplant Recipients
Anil A. Panackal et al. Volume 12, Number 3—March 2006

2004

Fungal Biofilms and Drug Resistance
Mary Ann Jabra-Rizk et al. Volume 10, Number 1—January 2004

2003

Noninvasive Method for Monitoring Pneumocystis carinii Pneumonia
Michael J. Linke et al. Volume 9, Number 12—December 2003 Sulfa Resistance and Dihydropteroate Synthase Mutants in Recurrent Pneumocystis carinii Pneumonia
Aimable Nahimana et al. Volume 9, Number 7—July 2003

2002

Cerebral Aspergillosis Caused by Neosartorya hiratsukae, Brazil
Josep Guarro et al. Volume 8, Number 9—September 2002

2001

Cryptococcus neoformans Infection in Organ Transplant Recipients: Variables Influencing Clinical Characteristics and Outcome
Shahid Husain et al. Volume 7, Number 3—June 2001