Volume 10, Number 1—January 2004
Research
Ciprofloxacin-resistant Salmonella enterica Typhimurium and Choleraesuis from Pigs to Humans, Taiwan
Po-Ren Hsueh*†
, Lee-Jene Teng*†, Sung-Pin Tseng*, Chao-Fu Chang‡, Jen-Hsien Wan†, Jing-Jou Yan†, Chun-Ming Lee†, Yin-Ching Chuang†, Wen-Kuei Huang†, Dine Yang†, Jainn-Ming Shyr†, Kwok-Woon Yu†, Li-Shin Wang†, Jang-Jih Lu†, Wen-Chien Ko†, Jiunn-Jong Wu†, Feng-Yee Chang†, Yi-Chueh Yang†, Yeu-Jun Lau†, Yung-Ching Liu†, Cheng-Yi Liu†, Shen-Wu Ho†, and Kwen-Tay Luh*†
, Lee-Jene Teng*†, Sung-Pin Tseng*, Chao-Fu Chang‡, Jen-Hsien Wan†, Jing-Jou Yan†, Chun-Ming Lee†, Yin-Ching Chuang†, Wen-Kuei Huang†, Dine Yang†, Jainn-Ming Shyr†, Kwok-Woon Yu†, Li-Shin Wang†, Jang-Jih Lu†, Wen-Chien Ko†, Jiunn-Jong Wu†, Feng-Yee Chang†, Yi-Chueh Yang†, Yeu-Jun Lau†, Yung-Ching Liu†, Cheng-Yi Liu†, Shen-Wu Ho†, and Kwen-Tay Luh*†Table 2
Characteristics of Salmonella enterica serotype Typhimurium isolates from humansa and pigs,b Taiwan
| Ciprofloxacin susceptibility (N) | MIC (μg/mL) (N) | Mutation at | Genotype: genosubtype | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| gyrA gene | parC gene | acrR gene | |||||||||||||
| Ser83Phe Asp87Gly (N) | Ser83Phe Asp87Asn (N) | Ser83Ph (N)e | Ser83Tyr (N) | Ser80Arg (N) | Glu84Lys (N) | Gln78Stp (N) | Arg107Cys (N) | ||||||||
| Humans | |||||||||||||||
| Resistant (26) | 16-64 | 24 | 2 | 0 | 0 | 24 | 2 | 0 | 0 | I (26), Ia (4), Ic (5), Id (6), Ie (1), If (1), Ig (2), Ih (1), Ii (1) Ij (1), Ik (2), Il (1) | |||||
| Susceptible (5) | 0.03-0.25 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | IIa (1), IIb (1), III (1), IV (1), V (1) | |||||
| Pigs | |||||||||||||||
| Resistant (2) | 128 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | I (2): Ic (1), Im (1) | |||||
aN = 31.
bN = 2.
