Volume 10, Number 1—January 2004
Research
Ciprofloxacin-resistant Salmonella enterica Typhimurium and Choleraesuis from Pigs to Humans, Taiwan
Po-Ren Hsueh*†
, Lee-Jene Teng*†, Sung-Pin Tseng*, Chao-Fu Chang‡, Jen-Hsien Wan†, Jing-Jou Yan†, Chun-Ming Lee†, Yin-Ching Chuang†, Wen-Kuei Huang†, Dine Yang†, Jainn-Ming Shyr†, Kwok-Woon Yu†, Li-Shin Wang†, Jang-Jih Lu†, Wen-Chien Ko†, Jiunn-Jong Wu†, Feng-Yee Chang†, Yi-Chueh Yang†, Yeu-Jun Lau†, Yung-Ching Liu†, Cheng-Yi Liu†, Shen-Wu Ho†, and Kwen-Tay Luh*†
, Lee-Jene Teng*†, Sung-Pin Tseng*, Chao-Fu Chang‡, Jen-Hsien Wan†, Jing-Jou Yan†, Chun-Ming Lee†, Yin-Ching Chuang†, Wen-Kuei Huang†, Dine Yang†, Jainn-Ming Shyr†, Kwok-Woon Yu†, Li-Shin Wang†, Jang-Jih Lu†, Wen-Chien Ko†, Jiunn-Jong Wu†, Feng-Yee Chang†, Yi-Chueh Yang†, Yeu-Jun Lau†, Yung-Ching Liu†, Cheng-Yi Liu†, Shen-Wu Ho†, and Kwen-Tay Luh*†Table 3
Characteristics of Salmonella. enterica serotype Choleraesuis isolates from humansaand pigsb in Taiwan
| Ciprofloxacin susceptibility (μg/mol) | MIC | Mutation at | Genotype: genosubtype (N) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| gyrA gene | parC gene | acrR gene | ||||||||
| Ser83Phe Asp87Asn (N) | Ser83Phe (N) | Asp87Asn (N) | Ser83Tyr (N) | Asp87Gyr (N) | Ser80Ile (N) | Gln78Stp (N) | Arg107Cys (N) | Ser83Phe (N) | ||
| Humans | ||||||||||
| Resistant (11) | 16–64 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | A (1); B (10): B1 (2), B2 (2), B3 (2), B4 (1), B5 (2), B6 (1) |
| Susceptible (5) | 0.03–0.25 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | C (1), D (1), E (1), F (1), G (1) |
| Pigs | ||||||||||
| Resistant (5) | 64 | 5 | 5 | 0 | 0 | 0 | 5 | 5 | 0 | 0 B (5): B2 (1), B5 (1), B8 (1), B9 (2) |
| Susceptible or intermediate (8) | 0.5–2 | 0 | 1 | 1 | 2 | 4 | 0 | 0 | 0 | B (2): B7 (1), B10 (1); H (1), I (1), J (3), K (1) |
aN = 16.
bN = 13.
