Volume 10, Number 1—January 2004
Research
Escherichia coli Producing CTX-M-2 β-Lactamase in Cattle, Japan
Yutaka Shiraki*
, Naohiro Shibata†, Yohei Doi†, and Yoshichika Arakawa†
, Naohiro Shibata†, Yohei Doi†, and Yoshichika Arakawa†Table 2
MICs of β-lactams for Escherichia coli strains isolated from cattle, transconjugants, and recipientsa
| MIC (μg/mL) for E. coli strain: | |||||
|---|---|---|---|---|---|
| Antimicrobial drug | GS528 | CSH2 trGS528 | GS554 | CSH2 trGS554 | CSH2 |
| Piperacillin | >64 | >64 | >64 | >64 | <16 |
| Cefotaxime | >128 | >128 | >128 | >128 | <0.5 |
| Cefotaxime + CLAb | <0.12 | <0.12 | 32 | 32 | <0.12 |
| Ceftazidime | 2 | 4 | 32 | 32 | <0.5 |
| Ceftazidime + CLA | <0.12 | <0.12 | 16 | 32 | <0.12 |
| Aztreonam | >64 | 64 | >64 | 64 | <0.5 |
| Ceftriaxone | >64 | >64 | >64 | >64 | <0.5 |
| Cefpodoxime | >64 | >64 | >64 | >64 | <0.5 |
| Cefepime | >32 | >32 | >32 | >32 | <1 |
| Cefotetan | <0.5 | <0.5 | >32 | >32 | <0.5 |
| Cefmetazole | 1 | 1 | >16 | >16 | 1 |
| Cefoxitin | <2 | <2 | >32 | >32 | <2 |
| Meropenem | <0.5 | <0.5 | 8 | 4 | <0.5 |
| Ceftiofur | >1,024 | >1,024 | >1,024 | >1,024 | <0.25 |
aE. coli CSH2 trGS528 and trGS554 were transconjugants of E. coli GS528 and GS554, respectively.
bCLA, clavulanic acid at a fixed concentration of 4 μg/mL.
