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Volume 10, Number 1—January 2004

Research

Escherichia coli Producing CTX-M-2 β-Lactamase in Cattle, Japan

Yutaka Shiraki*Comments to Author , Naohiro Shibata†, Yohei Doi†, and Yoshichika Arakawa†
Author affiliations: *Gifu Prefectural Office of Meat Inspection, Gifu, Japan; †National Institute of Infectious Diseases, Tokyo, Japan

Main Article

Table 2

MICs of β-lactams for Escherichia coli strains isolated from cattle, transconjugants, and recipientsa

MIC (μg/mL) for E. coli strain:
Antimicrobial drug GS528 CSH2
trGS528 GS554 CSH2
trGS554 CSH2
Piperacillin >64 >64 >64 >64 <16
Cefotaxime >128 >128 >128 >128 <0.5
Cefotaxime + CLAb <0.12 <0.12 32 32 <0.12
Ceftazidime 2 4 32 32 <0.5
Ceftazidime + CLA <0.12 <0.12 16 32 <0.12
Aztreonam >64 64 >64 64 <0.5
Ceftriaxone >64 >64 >64 >64 <0.5
Cefpodoxime >64 >64 >64 >64 <0.5
Cefepime >32 >32 >32 >32 <1
Cefotetan <0.5 <0.5 >32 >32 <0.5
Cefmetazole 1 1 >16 >16 1
Cefoxitin <2 <2 >32 >32 <2
Meropenem <0.5 <0.5 8 4 <0.5
Ceftiofur >1,024 >1,024 >1,024 >1,024 <0.25

aE. coli CSH2 trGS528 and trGS554 were transconjugants of E. coli GS528 and GS554, respectively.
bCLA, clavulanic acid at a fixed concentration of 4 μg/mL.

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