Correlating Epidemiologic Trends with the Genotypes Causing Meningococcal Disease, Maryland
M. Catherine McEllistrem* , John A. Kolano*, Margaret A. Pass†, Dominique A. Caugant‡, Aaron B. Mendelsohn§, Antonio Guilherme Fonseca Pacheco§, Jafar Razeq¶, Lee H. Harrison*†, and the Maryland Emerging Infections Program
Author affiliations: *University of Pittsburgh Graduate School of Public Health and School of Medicine, Pittsburgh, Pennsylvania, USA; †Johns Hopkins University Bloomberg School of Hygiene and Public Health, Baltimore, Maryland, USA; ‡World Health Organization Collaborating Centre for Reference and Research on Meningococci, Norwegian Institute of Public Health, Oslo, Norway; §University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, USA; ¶Maryland Department of Health and Mental Hygiene, Baltimore, Maryland, USA
Figure 2. Box-plot of mean pairwise similarities demonstrating the genetic relatedness of serogroup C strains for persons <14 years (32 strains), persons 15–24 years (28 strains), and adults ∃>25 years (14 strains) during 1992–1999. The lower, central, and upper horizontal lines in the box indicate the 25th, 50th, and 75th percentiles. The outliers, as defined as the 25th or 75th quartile ±1.5x the interquartile range, are plotted as circles. Notches of box plots that do not overlap indicate a statistically significant difference at the <0.05 level.
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