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Volume 10, Number 3—March 2004

Research

Neutralizing Antibodies and Sin Nombre Virus RNA after Recovery from Hantavirus Cardiopulmonary Syndrome

Chunyan Ye*, Joseph Prescott*, Robert A. Nofchissey*, Diane Goade*, and Brian Hjelle*Comments to Author 
Author affiliations: *University of New Mexico School of Medicine, Albuquerque, New Mexico, USA

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Table

Demographic and clinical characteristics of 21 patients with history of Sin Nombre virus infectiona

Patient Age at time of illness Sex Date admitted Day serum collected Location Severityb
1
10
M
30 Mar 1999
589
NM
I
2
44
F
4 Dec 1995
1789
NM
IIE
3
28
F
5 Apr 1999
592
NM
0
4
28
F
3 Apr 1999
566
WA
II
5
42
M
15 Jun 1999
94
NM
I
6
29
F
1 May 1998
1063
NM
I
7
18
F
11 Aug 1998
512
CO
IIE
8
44
F
29 Mar 1994
1627
NM
II
9
43
M
1 Sep 2000
231
AZ
IIE
10
41
M
20 Mar 1997
1436
KS
II
11
39
F
6 Mar 2001
85
NM
II
12
50
M
20 Aug 1998
334
NM
IIE
13
34
F
15 Jul 1999
92
CO
I
14
44
F
3 Nov 1997
1281
KS
II
15
19
F
18 Oct 2000
132
MT
II
16
27
M
23 Jul 1997
1356
NM
I
17
27
F
27 Jan 1998
1196
KS
I
18
23
F
30 Oct 1999
161
NM
IIE
19
16
M
19 Sep 1997
1419
TX
II NO (15)
20
21
F
27 May 1994
2268
NM
II
21 44 M 20 Dec 1997 1056 WI II

aF, female; M, male; NM, New Mexico, WA, Washington, CO, Colorado; AZ, Arizona; KS, Kansas; MT, Montana; TX, Texas; WI, Wisconsin.
bSeverity scale: Class 0, prodromal symptoms with seroconversion but with no cardiopulmonary manifestations; Class I, prodrome symptoms with hypoxia but not requiring endotracheal intubation; Class II, survived but required endotracheal intubation; Class IIE, required extracorporeal membrane oxygenation; II NO, treated with inhalational nitric oxide. Because they required endotracheal intubation, patients in Class II are regarded as having been more severely ill than those in Classes 0 and I.

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