Volume 10, Number 5—May 2004
Research
Clinical Manifestations, Laboratory Findings, and Treatment Outcomes of SARS Patients
Jann-Tay Wang*, Wang-Huei Sheng*, Chi-Tai Fang*, Yee-Chun Chen*, Jiun-Ling Wang*, Chong-Jen Yu*, Shan-Chwen Chang*
, and Pan-Chyr Yang*
, and Pan-Chyr Yang*Table 5
Univariate analysis of factors predictive for death and respiratory failure (logistic regression)a
| Factors | Odds ratio |
p value |
|||
|---|---|---|---|---|---|
| Mortality | ResF | Mortality | ResF | ||
| Age (every 1 y)b |
1.093 |
1.082 |
<0.001 |
<0.001 |
|
| Sex (male to female) |
3.086 |
2.841 |
0.064 |
0.036 |
|
| Severe underlying diseasec |
3.973 |
3.023 |
<0.001 |
<0.001 |
|
| Initial CRP levelb,c (every 1 mg/dL) |
1.300 |
1.391 |
0.004 |
<0.001 |
|
| Initial ANC count (every 0.1x109/L) |
1.022 |
1.031 |
0.020 |
0.006 |
|
| Initial lymphocyte count (every 0.1x109/L) |
0.091 |
0.916 |
0.188 |
0.162 |
|
| Initial platelet count (every 100x109/L) |
0.668 |
0.565 |
0.485 |
0.248 |
|
| Initial CXR findings (every one-lobe involvement) |
1.482 |
1.941 |
0.154 |
0.025 |
|
| Peak CRP level (every 1 mg/dL) |
1.193 |
1.385 |
0.033 |
<0.001 |
|
| Lowest lymphocyte count (every 0.1x109/L) |
0.801 |
0.804 |
0.079 |
0.032 |
|
| Peak LDH level (every 100 U/L) |
1.132 |
1.160 |
0.124 |
0.008 |
|
| Peak CK level (every 1 U/L) |
1.093 |
1.082 |
<0.001 |
<0.001 |
|
| Lowest platelet count (every 100x109/L) |
0.724 |
0.541 |
0.608 |
0.261 |
|
| Worst CXR findings (every one-lobe involvement) a | 1.505 | 2.147 | 0.064 | <0.001 | |
aResF, respiratory failure; CRP, C-reactive protein; ANC, absolute neutrophil count; CXR, chest radiography; LDH, lactate dehydrogenase; CK, creatine kinase.
bFactors that remained statistically significant after multivariate analysis for respiratory failure.
cFactors that remained statistically significant after multivariate analysis for death.
