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Volume 10, Number 5—May 2004

Research

Clinical Manifestations, Laboratory Findings, and Treatment Outcomes of SARS Patients

Jann-Tay Wang*, Wang-Huei Sheng*, Chi-Tai Fang*, Yee-Chun Chen*, Jiun-Ling Wang*, Chong-Jen Yu*, Shan-Chwen Chang*Comments to Author , and Pan-Chyr Yang*
Author affiliations: *National Taiwan University Hospital, Taipei, Taiwan

Main Article

Table 5

Univariate analysis of factors predictive for death and respiratory failure (logistic regression)a

Factors Odds ratio
p value
Mortality ResF Mortality ResF
Age (every 1 y)b
1.093
1.082
<0.001
<0.001
Sex (male to female)
3.086
2.841
0.064
0.036
Severe underlying diseasec
3.973
3.023
<0.001
<0.001
Initial CRP levelb,c (every 1 mg/dL)
1.300
1.391
0.004
<0.001
Initial ANC count (every 0.1x109/L)
1.022
1.031
0.020
0.006
Initial lymphocyte count (every 0.1x109/L)
0.091
0.916
0.188
0.162
Initial platelet count (every 100x109/L)
0.668
0.565
0.485
0.248
Initial CXR findings (every one-lobe involvement)
1.482
1.941
0.154
0.025
Peak CRP level (every 1 mg/dL)
1.193
1.385
0.033
<0.001
Lowest lymphocyte count (every 0.1x109/L)
0.801
0.804
0.079
0.032
Peak LDH level (every 100 U/L)
1.132
1.160
0.124
0.008
Peak CK level (every 1 U/L)
1.093
1.082
<0.001
<0.001
Lowest platelet count (every 100x109/L)
0.724
0.541
0.608
0.261
Worst CXR findings (every one-lobe involvement) a 1.505 2.147 0.064 <0.001

aResF, respiratory failure; CRP, C-reactive protein; ANC, absolute neutrophil count; CXR, chest radiography; LDH, lactate dehydrogenase; CK, creatine kinase.
bFactors that remained statistically significant after multivariate analysis for respiratory failure.
cFactors that remained statistically significant after multivariate analysis for death.

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