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Volume 10, Number 5—May 2004
Research

Causative Agent of Pogosta Disease Isolated from Blood and Skin Lesions

Satu Kurkela*†Comments to Author , Tytti Manni*, Antti Vaheri*†, and Olli Vapalahti*†‡
Author affiliations: *Haartman Institute, Helsinki, Finland; †HULAB, Helsinki, Finland; ‡University of Helsinki, Helsinki, Finland

Main Article

Figure 2

Phylogenetic tree is based on the nucleotide sequences of 1,178–1,281 bp from nsP3 and nsP4 region, nucleotides 5,258-6,510; the genome position is given according to the published sequence of the strain AR339 (HRsp variant) (2). The tree was constructed by using Neighbor-joining algorithms (NEIGHBOR). 5,000 bootstrap replicates were calculated. Only those bootstrap support values that exceed 50% are shown. The following sequences available in GenBank were included into the comparison: AR339 (HR

Figure 2. Phylogenetic tree is based on the nucleotide sequences of 1,178–1,281 bp from nsP3 and nsP4 region, nucleotides 5,258-6,510; the genome position is given according to the published sequence of the strain AR339 (HRsp variant) (2). The tree was constructed by using Neighbor-joining algorithms (NEIGHBOR). 5,000 bootstrap replicates were calculated. Only those bootstrap support values that exceed 50% are shown. The following sequences available in GenBank were included into the comparison: AR339 (HRsp variant); Egypt (J02363, J02364, J02365, J02366, J02367), Girdwood S.A.; South-Africa (U38304), MRE16; Malaysia (AF492770), Ockelbo (Edsbyn 82); Sweden (M69205), S.A.AR86; South-Africa (U38305), SW6562; Australia (AF429428), YN87448; China (AF103734) and XJ-160; China (AF103728).

Main Article

References
  1. Taylor  RM, Hurlbut  HS, Work  TH, Kingsbury  JR, Frothingham  TE. Sindbis virus: a newly recognized arthropod-transmitted virus. Am J Trop Med Hyg. 1955;4:8446.PubMedGoogle Scholar
  2. Strauss  EG, Rice  CM, Strauss  JH. Complete nucleotide sequence of the genomic RNA of Sindbis virus. Virology. 1984;133:92110. DOIPubMedGoogle Scholar
  3. Brummer-Korvenkontio  M, Vapalahti  O, Kuusisto  P, Saikku  P, Manni  T, Koskela  P, Epidemiology of Sindbis virus infections in Finland 1981–96: possible factors explaining a peculiar disease pattern. Epidemiol Infect. 2002;129:33545. DOIPubMedGoogle Scholar
  4. Turunen  M, Kuusisto  P, Uggeldahl  PE, Toivanen  A. Pogosta disease: clinical observations during an outbreak in the province of North Karelia, Finland. Br J Rheumatol. 1998;37:117780. DOIPubMedGoogle Scholar
  5. Lvov  DK, Vladimirtseva  EA, Butenko  AM, Karabatsos  N, Trent  DW, Calisher  CH. Identity of Karelian fever and Ockelbo viruses determined by serum dilution-plaque reduction neutralization tests and oligonucleotide mapping. Am J Trop Med Hyg. 1988;39:60710.PubMedGoogle Scholar
  6. Lvov  DK, Skvortsova  TM, Berezina  LK, Gromashevsky  VL, Yakovlev  BI, Gushchin  BV, Isolation of Karelian fever agent from Aedes communis mosquitoes. Lancet. 1984;2:399400. DOIPubMedGoogle Scholar
  7. Shirako  Y, Niklasson  B, Dalrymple  JM, Strauss  EG, Strauss  JH. Structure of the Ockelbo virus genome and its relationship to other Sindbis viruses. Virology. 1991;182:75364. DOIPubMedGoogle Scholar
  8. Skogh  M, Espmark  A. Ockelbo disease: epidemic arthritis-exanthema syndrome in Sweden caused by Sindbis-virus like agent. Lancet. 1982;1:7956. DOIPubMedGoogle Scholar
  9. Lundstrom  JO, Vene  S, Espmark  A, Engvall  M, Niklasson  B. Geographical and temporal distribution of Ockelbo disease in Sweden. Epidemiol Infect. 1991;106:56774. DOIPubMedGoogle Scholar
  10. Niklasson  B, Espmark  Å, LeDuc  JW, Gargan  TP, Ennis  WA, Tesh  RB, Association of a Sindbis-like virus with Ockelbo disease in Sweden. Am J Trop Med Hyg. 1984;33:12127.PubMedGoogle Scholar
  11. Lundström  JO, Lindström  KM, Olsen  B, Dufva  R, Krakower  DS. Prevalence of Sindbis virus neutralizing antibodies among Swedish passerines indicates that thrushes are the main amplifying hosts. J Med Entomol. 2001;38:28997. DOIPubMedGoogle Scholar
  12. Lundström  JO, Turell  MJ, Niklasson  B. Viremia in three orders of birds (Anseriformes, Galliformes and Passeriformes) inoculated with Ockelbo virus. J Wildl Dis. 1993;29:18995.PubMedGoogle Scholar
  13. Malherbe  H, Strickland-Cholmley  M, Jackson  AL. Sindbis virus infection in man. Report of a case with recovery of virus from skin lesions. S Afr Med J. 1963;37:54752.PubMedGoogle Scholar
  14. Zhou  G, Liang  G, Li  L. Complete nucleotide sequence of the nonstructural gene of alphavirus YN87448 strain isolated in China and its relationship to other Sindbis viruses. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 1999;13:31420.PubMedGoogle Scholar
  15. Hörling  J, Vene  S, Franzen  C, Niklasson  B. Detection of Ockelbo virus RNA in skin biopsies by polymerase chain reaction. J Clin Microbiol. 1993;31:20049.PubMedGoogle Scholar
  16. Vene  S, Franzen  C, Niklasson  B. Development of specific antibody patterns and clinical symptoms following Ockelbo virus infection. Arch Virol. 1994;134:6171. DOIPubMedGoogle Scholar
  17. Thompson  JD, Higgins  DG, Gibson  TJ. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, positions-specific gap penalties and weight matrix choice. Nucleic Acids Res. 1994;22:467380. DOIPubMedGoogle Scholar
  18. Niklasson  B, Espmark  A, Lundstrom  J. Occurrence of arthralgia and specific IgM antibodies three to four years after Ockelbo disease. J Infect Dis. 1998;157:8325.PubMedGoogle Scholar
  19. Heise  MT, Simpson  DA, Johnston  RE. Sindbis-group alphavirus replication in periosteum and endosteum of long bones in adult mice. J Virol. 2000;74:92949. DOIPubMedGoogle Scholar
  20. Luukkainen  R, Laine  M, Nirhamo  J. Chronic arthritis after Sindbis-related (Pogosta) virus infection. Scand J Rheumatol. 2000;29:399400. DOIPubMedGoogle Scholar
  21. Autio  P, Niemi  KM, Kariniemi  AL. An eruption associated with alphavirus infection. Br J Dermatol. 1996;135:3203. DOIPubMedGoogle Scholar
  22. Mackenzie  JS, Lindsay  MD, Coelen  RJ, Broom  AK, Hall  RA, Smith  DW. Arboviruses causing human disease in the Australasian zoogeographic region. Arch Virol. 1994;136:44767. DOIPubMedGoogle Scholar
  23. Doherty  RL, Bodey  AS, Carew  JS. Sindbis virus infection in Australia. Med J Aust. 1969;2:10167.PubMedGoogle Scholar
  24. Guard  RW, McAuliffe  MJ, Stallman  ND, Bramston  BA. Haemorrhagic manifestations with Sindbis infection. Case report. Pathology. 1982;14:8990. DOIPubMedGoogle Scholar
  25. Boughton  CR, Hawkes  RA, Naim  HM, Wild  J, Chapman  B. Arbovirus infections in humans in New South Wales. Seroepidemiology of the alphavirus group of togaviruses. Med J Aust. 1984;141:7004.PubMedGoogle Scholar
  26. Norder  H, Lundstrom  JO, Kozuch  O, Magnius  LO. Genetic relatedness of Sindbis virus strains from Europe, Middle East, and Africa. Virology. 1996;222:4405. DOIPubMedGoogle Scholar
  27. Buckley  A, Dawson  A, Moss  SR, Hinsley  SA, Bellamy  PE, Gould  EA. Serological evidence of West Nile virus, Usutu virus and Sindbis virus infection of birds in the UK. J Gen Virol. 2003;84:280717. DOIPubMedGoogle Scholar
  28. Sammels  LM, Lindsay  MD, Poidinger  M, Coelen  RJ, Mackenzie  JS. Geographic distribution and evolution of Sindbis virus in Australia. J Gen Virol. 1999;80:73948.PubMedGoogle Scholar

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Page updated: February 22, 2011
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