Volume 10, Number 6—June 2004
Research
Respiratory Picornaviruses and Respiratory Syncytial Virus as Causative Agents of Acute Expiratory Wheezing in Children
Tuomas Jartti*
, Pasi Lehtinen*, Tytti Vuorinen†, Riikka Österback†, Bernadette van den Hoogen‡, Albert D.M.E. Osterhaus‡, and Olli Ruuskanen*
, Pasi Lehtinen*, Tytti Vuorinen†, Riikka Österback†, Bernadette van den Hoogen‡, Albert D.M.E. Osterhaus‡, and Olli Ruuskanen*Table 1
Positive viral findings in 293 children hospitalized for acute expiratory wheezinga
| Virus | Virus antigen test; n = 293 | Virus culture; n = 292 | Virus PCR;b n = 291 | Virus serology; n = 266 | Total; n = 293 | |
|---|---|---|---|---|---|---|
| Respiratory syncytial virus (RSV) |
62 (21) |
58 (20) |
50 (18) |
56 (21) |
80 (27) |
|
| Enterovirus |
14 (5) |
59 (20) |
27 (10) |
72 (25) |
||
| Rhinovirus |
25 (9) |
65 (22) |
71 (24) |
|||
| Rhino/enterovirus |
1 (0.3) |
46 (16) |
46 (16) |
|||
| Parainfluenza virus type 1 |
8 (3) |
0 |
8 (3) |
|||
| Parainfluenza virus type 2 |
0 |
0 |
0 |
0 |
||
| Parainfluenza virus type 3 |
4 (1) |
1 (0.3) |
5 (2) |
|||
| Parainfluenza virus type 1 or 3 |
8 (3) |
4 (1) |
||||
| Adenovirus |
0 |
9 (3) |
6 (2) |
15 (5) |
||
| Human metapneumovirus |
12 (4) |
12 (4) |
||||
| Influenza A virus |
1 (0.3) |
1 (0.3) |
2 (0.8) |
3 (1) |
||
| Influenza B virus |
4 (1) |
2 (0.7) |
2 (0.8) |
4 (1) |
||
| Coronavirus |
0 |
4 (1) |
4 (1) |
|||
| Mixed viral infection |
57 (19) |
|||||
| Total | 79 (27) | 111 (38) | 236 (81) | 101 (38) | 258 (88) | |
aData are presented as number of samples positive (% of evaluated samples).
bFor RSV polymerase chain reaction (PCR), n = 279.
