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Volume 10, Number 6—June 2004

Research

Respiratory Picornaviruses and Respiratory Syncytial Virus as Causative Agents of Acute Expiratory Wheezing in Children

Tuomas Jartti*Comments to Author , Pasi Lehtinen*, Tytti Vuorinen†, Riikka Österback†, Bernadette van den Hoogen‡, Albert D.M.E. Osterhaus‡, and Olli Ruuskanen*
Author affiliations: *Turku University Hospital, Turku, Finland; †Turku University, Turku, Finland; ‡Erasmus Medical Center, Rotterdam, the Netherlands

Main Article

Table 1

Positive viral findings in 293 children hospitalized for acute expiratory wheezinga

Virus Virus antigen test; n = 293 Virus culture; n = 292 Virus PCR;b n = 291 Virus serology; n = 266 Total; n = 293
Respiratory syncytial virus (RSV)
62 (21)
58 (20)
50 (18)
56 (21)
80 (27)
Enterovirus

14 (5)
59 (20)
27 (10)
72 (25)
Rhinovirus

25 (9)
65 (22)

71 (24)
Rhino/enterovirus

1 (0.3)
46 (16)

46 (16)
Parainfluenza virus type 1
8 (3)
0


8 (3)
Parainfluenza virus type 2
0
0

0
0
Parainfluenza virus type 3
4 (1)
1 (0.3)


5 (2)
Parainfluenza virus type 1 or 3



8 (3)
4 (1)
Adenovirus
0
9 (3)

6 (2)
15 (5)
Human metapneumovirus


12 (4)

12 (4)
Influenza A virus
1 (0.3)
1 (0.3)

2 (0.8)
3 (1)
Influenza B virus
4 (1)
2 (0.7)

2 (0.8)
4 (1)
Coronavirus

0
4 (1)

4 (1)
Mixed viral infection




57 (19)
Total 79 (27) 111 (38) 236 (81) 101 (38) 258 (88)

aData are presented as number of samples positive (% of evaluated samples).
bFor RSV polymerase chain reaction (PCR), n = 279.

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