Volume 10, Number 6—June 2004
Research
Quinolone-resistant Campylobacter Infections in Denmark: Risk Factors and Clinical Consequences1
Jørgen Engberg*†
, Jakob Neimann‡, Eva Møller Nielsen§2, Frank Møller Aarestrup§, and Vivian Fussing*3
, Jakob Neimann‡, Eva Møller Nielsen§2, Frank Møller Aarestrup§, and Vivian Fussing*3Table 2
Prevalence of quinolone resistance in Campylobacter isolates according to destination of foreign travel within 7 days before onset of illnessa
| Originb | No. of patients | Susceptible | % resistant | Resistant | RR | 95% CI | p value |
|---|---|---|---|---|---|---|---|
| Domestic (Denmark) |
526 |
474 |
9.9 |
52 |
– |
– |
– |
| Southern Europe |
43 |
15 |
65.1 |
28 |
6.59 |
4.70 to 9.24 |
<0.001 |
| Northern Europe |
17 |
17 |
0 |
0 |
– |
– |
– |
| Western Europe |
18 |
10 |
44.4 |
8 |
4.50 |
2.52 to 8.01 |
<0.001 |
| Central/East Europe |
9 |
8 |
11.0 |
1 |
1.12 |
0.17 to 7.26 |
1.00 |
| East Mediterranean Europec |
13 |
6 |
53.8 |
7 |
5.45 |
3.09 to 9.59 |
<0.001 |
| South Asia |
12 |
5 |
58.3 |
7 |
5.90 |
3.43 to 10.16 |
<0.001 |
| Southeast Asia |
13 |
2 |
84.6 |
11 |
8.56 |
6.05 to 12.11 |
<0.001 |
| Middle Eastd |
5 |
2 |
60.0 |
3 |
6.07 |
2.84 to 12.99 |
0.009 |
| Africa |
5 |
3 |
40.0 |
2 |
4.05 |
1.34 to 12.21 |
0.08 |
| Other regions/subregionse |
17 |
9 |
47.1 |
8 |
4.76 |
2.70 to 8.39 |
<0.001 |
| No travel information | 297 | 249 | 16.2 | 48 | 1.63 | 1.13 to 2.36 | 0.011 |
aRelative risk (RR), p value, and 95% confidence interval (CI) were calculated for the different regions/subregions with domestically acquired infections as reference.
bCountry grouping according to the World Tourism Organization (9).
cExclusive of Turkey.
dExclusive of Egypt.
eOther regions/subregions each with less than five visits (% quinolone resistance): Australasia 1 (0); Caribbean 1 (0); North America 1 (0), South America 2 (100); North Asia 2 (50); unknown destination 1 (0); multiple subregions/regions 9 (56).
