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Volume 10, Number 6—June 2004

Research

Antimicrobial Resistance Incidence and Risk Factors among Helicobacter pylori–Infected Persons, United States

William M. Duck*, Jeremy Sobel*, Janet M. Pruckler*, Qunsheng Song*, David Swerdlow*, Cindy Friedman*, Alana Sulka*, Balasubra Swaminathan*, Tom Taylor*, Mike Hoekstra*, Patricia M. Griffin*, Duane Smoot†, Rick Peek‡, DavidC. Metz§, Peter B. Bloom¶, Steven Goldschmid¶, Julie Parsonnet#, George Triadafilopoulos#, Guillermo I. Perez-Perez**, Nimish Vakil††, Peter Ernst‡‡, Steve Czinn§§, Donald Dunne§§, and Ben D. Gold*
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †Howard University Medical Center, Washington, DC, USA; ‡Vanderbilt University Medical Center, Nashville, Tennessee, USA; §University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA; ¶Atlanta Veterans Affairs Medical Center, Atlanta, Georgia, USA; #Stanford University Medical Center, Palo Alto, California, USA; **New York University School of Medicine, New York, New York, USA; ††Sinai Samaritan Medical Center, Milwaukee, Wisconsin, USA; ‡‡University of Virginia, Charlottesville, Virginia, USA; §§University Hospitals of Cleveland, Cleveland, Ohio, USA; ¶¶Indiana University Medical Center, Indianapolis, Indiana, USA

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Table 6

Phase II stratified multivariate analysis of risk factors for resistance to >1 antimicrobial agent among H. pylori isolates submitted to HARP, 1998–2002a

Risk factor Hazard ratio (95% CI)
Black race
2.1 (1.1–3.8)
Age >57 y
0.6 (0.3–1.1)
Took antibiotics 12 mo before esphagogastro- duodenal endoscopy; 1.9 (0.9–3.7)

aN = 235; HARP, Helicobacter pylori Antimicrobial Resistance Project; CI, confidence interval.

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