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Volume 10, Number 6—June 2004

Research

Newborn Screening for Congenital Infectious Diseases

Eurico Camargo Neto*†‡Comments to Author , Rosélia Rubin†, Jaqueline Schulte†, and Roberto Giugliani*‡§
Author affiliations: *Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; †Nobel RIE Laboratory, Porto Alegre, Brazil; ‡Neonatal Screening Center, Porto Alegre, Brazil; §Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil

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Table 3

Pediatric decision and symptoms presented in patients with congenital cytomegalovirus

n Decision Symptoms
5
No treatment
Asymptomatic, clinical follow-up
6 Symptomatic; treated with ganciclovir Microcephaly, intracranial calcifications, deafness, failure to thrive, HSMa (initially investigated for galactosemia), progressive muscular atrophy, sepsis, low weight, difficulty swallowing (died), thrombocytopenia, leukopenia

aHSM, hepatosplenomegaly.

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