Antibiotics in Animal Feed and Spread of Resistant Campylobacter from Poultry to Humans
Nicole M. Iovine* and Martin J. Blaser*†
Author affiliations: Antibiotics in Animal Feed; *New York University School of Medicine, New York, New York, USA; †and New York Harbor Department of Veterans Affairs Medical Center, New York, New York, USA
Figure. Acquisition of fluoroquinolone (FQ)-resistant Campylobacter from poultry. Campylobacter species are part of the normal enteric flora of poultry and are not resistant to fluoroquinolones, unless these have been added to the poultry feed in subtherapeutic doses. These antimicrobial-exposed poultry become colonized with resistant Campylobacter strains but remain healthy. During the slaughter and processing of the poultry, meat can become contaminated with Campylobacter in fecal material, and the organisms survive on processed poultry sent to supermarkets. Human consumption of Campylobacter-contaminated meat may lead to infection, with potentially increased morbidity if the strain is fluoroquinolone-resistant.
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