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Volume 10, Number 7—July 2004

Research

Sporadic Cryptosporidiosis Case-Control Study with Genotyping

Paul R. Hunter*Comments to Author , Sara Hughes†, Sarah Woodhouse†, Qutub Syed†, Neville Q. Verlander‡, Rachel M. Chalmers§, Kenton Morgan¶, Gordon Nichols†, Nick Beeching#, and Keith Osborn**
Author affiliations: *University of East Anglia, Norwich United Kingdom; †Communicable Disease Surveillance Centre – North West, Chester, United Kingdom; ‡Communicable Disease Surveillance Centre, London, United Kingdom; §Singleton Hospital, Swansea, United Kingdom; ¶University of Liverpool, Liverpool, United Kingdom; #Liverpool School of Tropical Medicine, Liverpool, United Kingdom; and; **United Utilities, Warrington, United Kingdom

Main Article

Table 3

Final multivariable model for Cryptosporidium hominis infectiona,b

Variables Adjusted OR 95% CI p value
Health authority



   A 1 < 0.001
   B 0.030 0.003–0.335
   C n.e. n.e.
   D 0.781 0.206–2.960
   E 0.002 0–∞
   F 0.169 0.034–0.836
   G 0.277 0.022–3.516
   H 0.229 0.019–2.734
   I n.e. n.e.
   J 0.072 0.011–0.456
   K n.e. n.e.
   L 0.398 0.025–6.396
   M 2.116 0.573–7.809
   N 5.321 1.098–25.78
   O 0.169 0.017–1.685
   P 0.001 0–∞
   Q n.e. n.e.
   R 0.126 0.020–0.809
   S 0.408 0.065–2.539
   T 1.488 0.273–8.104
   U
1.015
0.288–3.579

Age
0.997/y
0.982–1.012
0.713
Travel outside UK



   Y 6.841 2.622–17.850 < 0.001
   N
1.000


Spend time sleeping or sitting outside on the ground



   Y 0.241 0.060–0.968 0.027
   N
1.000


Diaper changing contact with a child <5 y of age



   Y 3.991 1.848–8.618 < 0.001
   N
1.000


Usually wash before eating raw fruit and vegetables



   Always 1.000 0.022
   Usually 0.347 0.159–0.757
   Sometimes 0.967 0.437–2.139
   Never
1.337
0.387–4.629

No. of times swum in a toddler pool
1.258 per time
0.960–1.649
0.077
No. of persons 5–15 y of age living with you
0.639 per person
0.413–0.991
0.037
Eat fresh fruit



   Y 0.222 0.058–0.852 0.027
   N 1.000

aEstimated from 433 observations (82 case-patients and 351 controls).
bOR, odds ratio; CI, confidence interval; NE, not estimable.

Main Article

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