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Volume 10, Number 7—July 2004

Research

Rapid Assessment Tool for Haemophilus influenzae type b Disease in Developing Countries1

Daniel R. Feikin*Comments to Author , Christopher B. Nelson†, James P. Watt*‡, Ezzeddine Mohsni§, Jay D. Wenger†, and Orin S. Levine*‡
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †World Health Organization, Geneva, Switzerland; ‡Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA; §World Health Organization, Cairo, Egypt

Main Article

Table 1

Results of Haemophilus influenzae type b (Hib) rapid assessment tool in 11 developing countries

Country % culture-confirmeda Meningitis incidence rate method (MIR)
Ratio meningitis cases U5MR:MIR
Hib meningitis rateb Hib meningitis ratec Cases/deathsd Cases/deathse
Ghana
na
0
72f
2,030/609
10,148/2,030
2.7
Uganda
50
44
59
2,533/633
12,663/759
1.1
Egypt
50
1
23
1,795/682
8,977/539
3.7
Iran
67
5
7
599/12
2,994/180
3.3
Jordan
43
6
14
107/5
534/27
2.9
Morocco
44
6
23
689/34
3,443/172

Oman
43g
27
41
112/11
560/34
0.43
Yemen
NA
0
23h
790/245
3,950/897
3.9
Kyrgyzstan
33
15
20
101/12
505/51
1.2
Uzbekistan
NA
0
4j
103/12
515/52
5.4
Bhutan 42 6 15 16/5 80/8 3.4

aMeningitis caused by Hib.
bUnadjusted meningitis incidence rate is the number of culture-confirmed Hib meningitis cases per 100,000 children <5 years of age in the study site without making any of the adjustments accounted for in the rapid assessment tool (see Methods).
cAdjusted meningitis incidence rate is the number of Hib meningitis cases per 100,000 children <5 years of age in the study site, as determined by the rapid assessment tool (see Methods).
dNational Hib meningitis.
eNational Hib pneumonia.
gBased on Gram stain of coccobacilli.
hBased on literature review and use of data from hospital.
iUnder-5 mortality rate excludes neonatal deaths.
jBased on use of data from Moscow study and rate of lumbar puncture in Uzbekistan.

Main Article

1Some of the content of this manuscript has previously been presented in a document on the Web site of the World Health Organization (http://www.who.int/vaccines-documents/DocsPDF01/www625.pdf).

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