Volume 10, Number 7—July 2004
Research
Detection of SARS-associated Coronavirus in Throat Wash and Saliva in Early Diagnosis
Wei-Kung Wang*†, Shey-Ying Chen†1, I-Jung Liu*1, Yee-Chun Chen†, Hui-Ling Chen*, Chao-Fu Yang*, Pei-Jer Chen*, Shiou-Hwei Yeh‡, Chuan-Liang Kao*, Li-Min Huang†, Po-Ren Hsueh†, Jann-Tay Wang†, Wang-Hwei Sheng†, Chi-Tai Fang†, Chien-Ching Hung†, Szu-Min Hsieh†, Chan-Ping Su†, Wen-Chu Chiang†, Jyh-Yuan Yang§, Jih-Hui Lin§, Szu-Chia Hsieh*, Hsien-Ping Hu*, Yu-Ping Chiang*, Jin-Town Wang*, Pan-Chyr Yang†, Shan-Chwen Chang†
, and members of the SARS Research Group of the National Taiwan UniversityNational Taiwan University Hospital
, and members of the SARS Research Group of the National Taiwan UniversityNational Taiwan University HospitalTable 1
Severe acute respiratory syndrome–associated coronavirus (SARS-CoV) RNA in cell-free and cell-associated components of throat wash from probable SARS cases
| Patient IDa | Sampling dayb | Copies/5 mL throat wash (% of total) |
|
|---|---|---|---|
| Cell-free component | Cell-associated component | ||
| 1 |
d2 |
848,000 (99.6) |
2,982 (0.4) |
| 2 |
d3 |
34,320 (99.7) |
85 (0.3) |
| 3 |
d3 |
10,680 (99.7) |
34 (0.3) |
| 4 |
d3 |
119,500 (98.8) |
1,495 (1.2) |
| 5 |
d3 |
18,160 (99.6) |
72 (0.4) |
| 6 |
d4 |
14,400 (95.4) |
695 (4.6) |
| 7 |
d4 |
631,280 (99.9) |
416 (0.1) |
| 8 |
d4 |
19,900 (99.4) |
124 (0.6) |
| 9 |
d4 |
17,800 (99.5) |
91 (0.5) |
| 10 |
d5 |
40,500 (99.9) |
60 (0.1) |
| 11 |
d5 |
3,152,000 (99.2) |
25,146 (0.8) |
| 12 |
d6 |
1,896,000 (99.4) |
12,160 (0.6) |
| 13 |
d6 |
11,100 (99.6%) |
40 (0.4) |
| 14 |
d6 |
5,992 (99.4) |
35 (0.6) |
| 16 |
d8 |
33,400,000 (88.8) |
4,222,000 (11.2) |
| 17 | d9 | 13,192 (97.5) | 330 (2.5) |
aPatients of probable SARS were diagnosed according to the World Health Organization clinical definitions (15).
bSampling day 2 (d2) is the second day of fever.
