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Volume 10, Number 7—July 2004

Research

Detection of SARS-associated Coronavirus in Throat Wash and Saliva in Early Diagnosis

Wei-Kung Wang*†, Shey-Ying Chen†1, I-Jung Liu*1, Yee-Chun Chen†, Hui-Ling Chen*, Chao-Fu Yang*, Pei-Jer Chen*, Shiou-Hwei Yeh‡, Chuan-Liang Kao*, Li-Min Huang†, Po-Ren Hsueh†, Jann-Tay Wang†, Wang-Hwei Sheng†, Chi-Tai Fang†, Chien-Ching Hung†, Szu-Min Hsieh†, Chan-Ping Su†, Wen-Chu Chiang†, Jyh-Yuan Yang§, Jih-Hui Lin§, Szu-Chia Hsieh*, Hsien-Ping Hu*, Yu-Ping Chiang*, Jin-Town Wang*, Pan-Chyr Yang†, Shan-Chwen Chang†Comments to Author , and members of the SARS Research Group of the National Taiwan UniversityNational Taiwan University Hospital

Author affiliations: *National Taiwan University, Taipei, Taiwan; †National Taiwan University Hospital, Taipei, Taiwan; ‡National Health Research Institute, Taipei, Taiwan; §Center for Disease Control, Department of Health, Taipei, Taiwan; 1S.-Y. Chen and I-J. Liu contributed equally to the work.

Main Article

Table 1

Severe acute respiratory syndrome–associated coronavirus (SARS-CoV) RNA in cell-free and cell-associated components of throat wash from probable SARS cases

Patient IDa Sampling dayb Copies/5 mL throat wash (% of total)
Cell-free component Cell-associated component
1
d2
848,000 (99.6)
2,982 (0.4)
2
d3
34,320 (99.7)
85 (0.3)
3
d3
10,680 (99.7)
34 (0.3)
4
d3
119,500 (98.8)
1,495 (1.2)
5
d3
18,160 (99.6)
72 (0.4)
6
d4
14,400 (95.4)
695 (4.6)
7
d4
631,280 (99.9)
416 (0.1)
8
d4
19,900 (99.4)
124 (0.6)
9
d4
17,800 (99.5)
91 (0.5)
10
d5
40,500 (99.9)
60 (0.1)
11
d5
3,152,000 (99.2)
25,146 (0.8)
12
d6
1,896,000 (99.4)
12,160 (0.6)
13
d6
11,100 (99.6%)
40 (0.4)
14
d6
5,992 (99.4)
35 (0.6)
16
d8
33,400,000 (88.8)
4,222,000 (11.2)
17 d9 13,192 (97.5) 330 (2.5)

aPatients of probable SARS were diagnosed according to the World Health Organization clinical definitions (15).
bSampling day 2 (d2) is the second day of fever.

Main Article

1S.-Y. Chen and I.-J. Liu contributed equally to the work.

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