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Volume 10, Number 7—July 2004

Research

Detection of SARS-associated Coronavirus in Throat Wash and Saliva in Early Diagnosis

Wei-Kung Wang*†, Shey-Ying Chen†1, I-Jung Liu*1, Yee-Chun Chen†, Hui-Ling Chen*, Chao-Fu Yang*, Pei-Jer Chen*, Shiou-Hwei Yeh‡, Chuan-Liang Kao*, Li-Min Huang†, Po-Ren Hsueh†, Jann-Tay Wang†, Wang-Hwei Sheng†, Chi-Tai Fang†, Chien-Ching Hung†, Szu-Min Hsieh†, Chan-Ping Su†, Wen-Chu Chiang†, Jyh-Yuan Yang§, Jih-Hui Lin§, Szu-Chia Hsieh*, Hsien-Ping Hu*, Yu-Ping Chiang*, Jin-Town Wang*, Pan-Chyr Yang†, Shan-Chwen Chang†Comments to Author , and members of the SARS Research Group of the National Taiwan UniversityNational Taiwan University Hospital

Author affiliations: *National Taiwan University, Taipei, Taiwan; †National Taiwan University Hospital, Taipei, Taiwan; ‡National Health Research Institute, Taipei, Taiwan; §Center for Disease Control, Department of Health, Taipei, Taiwan; 1S.-Y. Chen and I-J. Liu contributed equally to the work.

Main Article

Table 2

Clinical information and SARS-CoV RNA in throat wash and saliva from probable SARS case-patientsa

Patient IDb Age
(y) Sex Sampling dayc Clinical information at sampling day
Fever Cough Dyspnea Chest x-ray infiltrate Throat wash
(copies/mL) Saliva
(copies/mL)
1
 52
 M
 d2
 Yes
 Yes
 Nod
 Yes
 1.58 x 105
 2.64 x 107
2
 28
 F
 d3
 Yes
 No
 No
 Yes
 4.69 x 103
 1.12 x 105
3
 47
 F
 d3
 Yes
 No
 Nod
 Yes
 1.56 x 103
 1.06 x 105
4
 42
 M
 d3
 Yes
 No
 No
 Yes
 2.39 x 104
 8.22 x 104
5
 26
 M
 d3
 Yes
 Yes
 No
 No
 3.56 x 103
 1.22 x 104
6
 32
 F
 d4
 Yes
 No
 No
 Yes
 2.88 x 103
 7.08 x 103
7
 48
 M
 d4
 Yes
 Yes
 No
 Yes
 1.32 x 103
 9.05 x 104
8
 46
 M
 d4
 Yes
 No
 No
 No
 3.98 x 103
 NA
9
 41
 F
 d4
 Yes
 No
 Nod
 No
 3.56 x 103
 NA
10
 47
 M
 d5
 Yes
 No
 No
 Yes
 8.10 x 103
 9.24 x 104
11
 52
 M
 d5
 Yes
 No
 Yesd
 Yes
 4.10 x 105
 1.74 x 107
12
 54
 M
 d6
 Yes
 Yes
 No
 Yes
 2.46 x 105
 6.38 x 108
13
 48
 F
 d6
 Yes
 No
 No
 Yes
 2.22 x 103
 1.78 x 105
14
 26
 F
 d6
 Yes
 No
 No
 Yes
 9.73 x 102
 9.52 x 103
15
 21
 F
 d7
 Yes
 Yes
 No
 No
 1.74 x 103
 NA
16
 28
 M
 d8
 Yes
 No
 No
 Yes
 5.93 x 106
 4.14 x 107
17 25 F d9 Yes No Yes Yes 9.58 x 102 2.80 x 104

aSARS-CoV, severe acute respiratory syndrome–associated coronavirus; M, male; F, female; NA = not available.
bPatients with probable SARS were diagnosed according to the World Health Organization clinical definitions (15).
cSampling day 2 (d2) is the second day of fever.
dIntubation for hypoxia was performed during the course of hospitalization.

Main Article

1S.-Y. Chen and I.-J. Liu contributed equally to the work.

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