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Volume 10, Number 8—August 2004

Research

Human Herpesviruses 6 and 7 and Central Nervous System Infection in Children1

Asad Ansari*†2, Shaobing Li*, Mark J. Abzug*†, and Adriana Weinberg*†Comments to Author 
Author affiliations: *University of Colorado School of Medicine, Denver, Colorado, USA; †The Children’s Hospital, Denver, Colorado, USA; 1This study was presented in part at the Pediatric Academic Societies’ Annual Meeting, Baltimore, Maryland, May 2002.; 2Current affiliation: Avera Regional Hospital, Sioux Falls, South Dakota, USA.

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Table 1

Characteristics of the study population with available clinical dataa

Characteristic No. patients (%)
Demographic

Age: median (range)
43 days (0–5,948 days)
<2 y
148 (68)
2–6 y
28 (13)
>6 y
42 (19)
Male:female
1.1:1
Clinical and laboratory

Fever
121 (56)
Rash
24 (11)
Seizures
53 (25)
Seizure disorder
29 (55)
Febrile
7 (13)
Metabolic
5 (9)
Infectious/postinfectious
5 (9)
Intracranial bleed
4 (8)
Hypoxia
3 (6)
Meningitis
61 (28)
Encephalitis
21 (10)
CSF pleocytosis
90 (43)
Immunocompromised 19 (9)

aN = 218; CSF, cerebrospinal fluid.

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