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Volume 10, Number 8—August 2004

Research

Mycobacterium ulcerans Disease (Buruli ulcer) in Rural Hospital, Southern Benin, 1997–2001

Martine Debacker*, Julia Aguiar†, Christian Steunou†, Claude Zinsou*†, Wayne M. Meyers‡, Augustin Guédénon§, Janet T. Scott*, Michèle Dramaix¶, and Françoise Portaels*Comments to Author 
Author affiliations: *Institute of Tropical Medicine, Antwerp, Belgium; †Centre Sanitaire et Nutritionnel Gbemoten, Zagnanado, Benin; ‡Armed Forces Institute of Pathology, Washington, DC, USA; §Ministère de la Santé, Cotonou, Benin; ¶Ecole de Santé Publique, Brussels, Belgium

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Table 3

Clinical signs and symptoms of Buruli ulcer by year

Clinical form 1997, n (%) 1998, n (%) 1999, n (%) 2000, n (%) 2001, n (%) Total, n (%)
Nodule 35 (12.1) 35 (10.1) 13 (3.5) 20 (7.2) 19 (5.9) 122 (7.6)
Edema 1 (0.3) 6 (1.7) 1 (0.3) 3 (1.1) 1 (0.3) 12 (0.7)
Plaque 66 (22.8) 98 (28.2) 123 (32.9) 72 (25.9) 111 (34.4) 470 (29.1)
Ulcer 119 (41.0) 99 (28.4) 109 (29.1) 72 (25.9) 59 (18.3) 458 (28.4)
Bone 29 (10.0) 23 (6.6) 31 (8.3) 16 (5.8) 23 (7.1) 122 (7.6)
Mixed 36 (12.4) 69 (19.8) 78 (20.9) 79 (28.4) 80 (24.8) 342 (21.2)
Healed ulcer 4 (1.4) 14 (4.0) 14 (3.7) 15 (5.4) 29 (9.0) 76 (4.7)
Other 0 4 (1.1) 4 (1.1) 1 (0.4) 0 9 (0.6)
Total bonea 40 (13.8) 49 (14.1) 55 (14.7) 35 (12.6) 34 (10.5) 213 (13.2)
Total 290 348 373 278 322 1611

aCombined osteomyelitis with no associated active cutaneous form and mixed forms with bone lesions.

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