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Volume 10, Number 8—August 2004

Dispatch

Syphilis in the HIV Era

Sigall Kassutto*Comments to Author  and John P. Doweiko*
Author affiliations: *Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

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Table

Selected laboratory results 1 month after therapy for neurosyphilis in HIV-positive patient with neurosyphilisa

Laboratory test Result
Complete blood count
Leukocytes 5,700/μL
Hematocrit 36%
Platelets 295,000/μL
Electrolytes and renal function tests Within normal limits
Liver function tests Within normal limits
Cerebrospinal fluid evaluation
Leukocytes 8 cells/μL
Differential 100% lymphocytes
Erythrocytes 9 cells/μL
Protein 33 mg/dL
Glucose 78 mg/dL
CSF-VDRL negative
HIV-1 testing
ELISA + WB positive
CD4 count 899 cells/μL
Viral load (RT-PCR) 878 copies/mL
Rapid plasma reagin testing
Baseline 1:128
1 month posttreatment 1:32
3 months posttreatment Nonreactive

aCSF-VDRL, cerebrospinal fluid venereal disease research laboratory test; ELISA, enzyme-linked immunosorbent assay; WB, Western blot; RT-PCR, reverse transcription–polymerase chain reaction.

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