Emerging Infectious Disease ISSN: 1080-6059

Recombinant Human Enterovirus 71 in Hand, Foot and Mouth Disease Patients

Yoke-Fun Chan* and Sazaly AbuBakar*

Author affiliations: *University of Malaya, Kuala Lumpur, Malaysia

Appendix Figure

Phylogenetic trees showing genetic relationships among Human Enterovirus 71 (HEV71) isolates. The neighbor-joining trees were constructed from alignment of nucleotide sequences of P1 (nt 747-3332) (panel A) and P2 (nt 3333-5066) (panel B). Bootstrap values are shown as percentage derived from 1,000 samplings, and the scale reflects the number of nucleotide substitutions per site along the branches. Isolates from fatal cases are denoted with asterisks.

Appendix Figure. Phylogenetic trees showing genetic relationships among Human Enterovirus 71 (HEV71) isolates. The neighbor-joining trees were constructed from alignment of nucleotide sequences of P1 (nt 747-3332) (panel A) and P2 (nt 3333-5066) (panel B). Bootstrap values are shown as percentage derived from 1,000 samplings, and the scale reflects the number of nucleotide substitutions per site along the branches. Isolates from fatal cases are denoted with asterisks.

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