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Volume 10, Number 9—September 2004


Yellow Fever Virus Infectivity for Bolivian Aedes aegypti Mosquitoes

John-Paul Mutebi*, Alberto Gianella†, Amelia Travassos da Rosa‡, Robert B. Tesh‡, Alan D. T. Barrett‡, and Stephen Higgs‡Comments to Author 
Author affiliations: *Chicago Department of Public Health, Chicago, Illinois, USA; †CENETROP, Santa Cruz, Bolivia; ‡University of Texas Medical Branch, Galveston, Texas, USA

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Table 1

Infection, dissemination, and virus titers for three strains of yellow fever virus, CENETROP-322, Jimenez, and Asibi, in two strains of Aedes aegypti mosquitoes, Santa Cruz and REX-D, at day 15 postinfectiona

Ae. aegypti Virus strain Hamster serum titer (TCID50 log10/mL) No. infected by titration (5%) Mean titer of positives (TCID50 log10/mL) Dissemination rate by IFA (%)
Santa Cruz CENETROP-322 8.5 10/10 (100) 3.5 20
Santa Cruz Jimenez 8.7 29/31 (93.5) 3.5 34.5
Santa Cruz Asibi 7.3 3/26 (15.1) 3.5 0
REX-D CENETROP-322 8.5 19/30 (63.3) 1.5 80.7
REX-D Jimenez 8.7 27/30 (90) 3.5 73.4
REX-D Asibi 7.3 13/30 (43.3) 4.0 38.4

aTCID50, tissue culture infectious dose 50%; IFA, immunofluorescence assay.

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