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Volume 10, Number 9—September 2004

Letter

Vancomycin Heteroresistance in Methicillin-resistant Staphylococcus aureus, Taiwan

Jiun-Ling Wang*, Sung-Pin Tseng*, Po-Ren Hsueh*Comments to Author , and Keiichi Hiramatsu†
Author affiliations: *National Taiwan University Hospital, Taipei, Taiwan; †Juntendo University School of Medicine, Tokyo, Japan

Main Article

Table

Characteristics of 21 methicillin-resistant Staphylococcus aureus isolates recovered from two patients with recurrent bacteremiaa

Designation of isolate Date of isolation (mo/day/year) Vancomycin MIC (μg/mL)
Teicoplanin MIC (μg/mL)
Etest
Broth microdilution
Agar dilution
Agar dilution
BHI BHI MHB BHI MHA MHA
Patient A (89-y-old man)
  A1 6/30/2000 3 2 1 2 2 2
  A2 6/14/2001 4 3 1 2 2 2
  A3 11/19/2001 4 4 2 2 2 2
  A4 3/5/2002 4 3 1 2 2 4
  A5 3/22/2002 4 3 2 3 2 4
  A6 4/3/2002 6 5 4 4 2 4
  A7 4/14/2002 6 5 4 4 3 4
  A8 4/29/2002 5 4 2 4 3 8
  A9 4/29/2002 6 3 2 4 3 4
  A10 5/7/2002 6 4 2 4 2 4
Patient B (72-y-old man)
  B1 4/26/2000 3 2 1 2 1 2
  B2 5/6/2000 4 2 1 2 2 8
  B3 5/18/2000 6 4 2 4 3 8
  B4 5/29/2000 5 4 1 4 2 8
  B5 6/15/2000 6 3 2 4 3 8
  B6 6/24/2000 8 4 2 4 3 8
  B7 7/19/2000 8 4 3 5 3 8
  B8 1/9/2001 4 1 1 2 1 1
  B9 1/26/2001 4 2 1 2 1 1
  B10 3/21/2001 3 2 1 2 1 1
  B11 4/6/2001 4 2 1 2 1 1
  Mu3 3 3 2 3 2
  Mu50 10 8 5 8 4

aBHI, brain heart infusion; MHB, Mueller-Hinton broth; MHA, Mueller-Hinton agar.

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