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Volume 11, Number 4—April 2005
Research

Childhood Hemolytic Uremic Syndrome, United Kingdom and Ireland

Richard M. Lynn*, Sarah J. O’Brien†1Comments to Author , C. Mark Taylor‡, Goutam K. Adak†, Henrik Chart§, Tom Cheasty§, John E. Coia¶, Iain A. Gillespie†, Mary E. Locking#, William J. Reilly#, Henry R. Smith§, Aoife Waters**, and Geraldine A. Willshaw§
Author affiliations: *Royal College of Paediatrics and Child Health, London, United Kingdom; †Communicable Disease Surveillance Centre, London, United Kingdom; ‡Birmingham Children’s Hospital, Birmingham, United Kingdom; §Health Protection Agency Centre for Infections, London, United Kingdom; ¶Western General Hospital, Edinburgh, United Kingdom; #Scottish Centre for Infection and Environmental Health, Glasgow, United Kingdom; and; **The Children’s Hospital, Dublin, Ireland

Main Article

Table 3

Properties of STEC strains of Escherichia coli serogroup O157 from patients <16 years of age with HUS with and without diarrhea compared with STEC O157 strains from all infected children <16 years of age, 1997–2001*

Phage type STEC-infected cases with HUS with diarrhea STEC-infected cases with HUS without diarrhea All STEC-
infected cases % Relative risk versus all other phage types (95% CI)
England, Wales, and Scotland
  2 86 537 623 14 1.59 (1.23–2.05)
  21/28 101 592 693 15 1.80 (1.41–2.31)
  8 1 236 237 0.4 0.04 (0.005–0.26)
  32 4 159 163 2 0.22 (0.09–0.6)
  4 9 126 135 7 0.64 (0.34–1.22)
  Others 19 296 315 6 –
  Total 220 1,946 2,166 10 –
England and Wales
  2 77 475 552 14 1.72 (1.3–2.28)
  21/28 67 357 424 16 1.96 (1.47–2.6)
  8 1 209 210 0.5 0.04 (0.006–0.3)
  32 3 145 148 2 0.19 (0.06–0.58)
  4 8 118 126 6 0.62 (0.31–1.23)
  Others 16 248 264 6 –
  Total 172 1,552 1,724 10 –
Scotland
  2 9 62 71 13 1.21 (0.61–2.38)
  21/28 34 235 269 13 1.56 (0.86–2.82)
  8 0 27 27 0 –
  32 1 14 15 7 0.61 (0.09–4.1)
  4 1 8 9 11 1.02 (0.16-6.62)
  Others 3 48 51 6 –
  Total 48 394 442 11 –

*STEC, Shiga toxin–producing Escherichia coli; HUS, hemolytic uremic syndrome; CI, confidence interval.

Main Article

1Current affiliation: University of Manchester, Salford, United Kingdom

Page created: May 23, 2011
Page updated: May 23, 2011
Page reviewed: May 23, 2011
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